Keyphrases
TAK1 Inhibitor
100%
Orally Bioavailable
50%
Blood-brain Barrier
50%
Penetrant
50%
Novel Treatments
50%
Alzheimer's Disease
50%
Small Molecules
50%
TAK1
50%
Attribute Profiles
16%
Tauopathy Model
16%
Target Product Profile
16%
Neuronal Pyroptosis
16%
PS19 Mice
16%
Preclinical Candidate
16%
PS19
16%
Dorsal Dentate Gyrus
16%
Therapeutic Potential
8%
Cognitive Decline
8%
Treatment Options
8%
New Drug Targets
8%
Mouse Model
8%
Canonical Wnt Signaling
8%
Grant Proposal
8%
Central Nervous System
8%
Novel Therapeutic Targets
8%
Neuronal Death
8%
Penetrance
8%
Optimal Target
8%
Safety Study
8%
AD Mouse Model
8%
State Universities
8%
Effective Therapy
8%
Disease Progression
8%
Phosphorylation Reaction
8%
Successful Outcome
8%
Hippocampal Neurons
8%
First-in-class
8%
North Carolina
8%
Global Health Issue
8%
Biochemistry, Genetics and Molecular Biology
Small Molecule
50%
Mouse Model
50%
Blood Brain Barrier
50%
Necroptosis
50%
Penetrance
25%
Phosphotransferase
25%
Kinase
25%
Mediator
25%
Pharmacology, Toxicology and Pharmaceutical Science
Blood-Brain Barrier
50%
Alzheimer's Disease
50%
Mouse Model
50%
Tauopathy
50%
Disease Exacerbation
25%
Phosphotransferase
25%