Keyphrases
Positive Allosteric Modulator
100%
Cognitive Decline
50%
D1 Dopamine Receptor
50%
Thiophene
41%
Allosteric Site
25%
Pyrimidone
25%
Sub-optimum
16%
Compound B
16%
Pharmacological Characterization
16%
Chemotype
16%
Therapeutic Leads
16%
Dopamine
12%
Cognitive Function
12%
High-throughput Screening
8%
Prefrontal Cortex
8%
Inverted-U
8%
Chemical Tools
8%
Hit Compound
8%
Dopamine Ligands
8%
Orthosteric
8%
U-hypothesis
8%
Allosteric Binding Site
8%
Reduced Tolerances
8%
Bristol-Myers Squibb
8%
Effective Concentration
8%
Therapeutic Translation
8%
Optimum Performance
8%
Eli Lilly
8%
New Scaffolds
8%
Two-hit
8%
Agonism
8%
Neuroscience
Positive Allosteric Modulator
100%
Dopamine Receptor D1
50%
Thiophene
41%
Allosteric Site
25%
Cognitive Function
12%
Prefrontal Cortex
8%
Alzheimer's Disease
8%
Binding Site
8%
Agonist
8%
Pharmacology, Toxicology and Pharmaceutical Science
Positive Allosteric Modulator
100%
Dopamine 1 Receptor
50%
Thiophene
41%
Binding Site
8%
Alzheimer's Disease
8%
High-Throughput Screening
8%