Detalles del proyecto
Descripción
The Carolina Center for Computational Toxicology (http://comptox.us/) EXIT is a broad, interdisciplinary partnership with a mission to devise novel experimental approaches and computational tools/methods with direct relevance to EPA's research and regulatory objectives. We will continue our productive research in support of Tox21 and NexGen by focusing on the following Objectives: (1) Develop a quantitative high-throughput screening (qHTS) approach to probe differential chemical effects in a population-based in vitro system; (2) Provide the computational toxicology solutions for risk characterization in NexGen assessments with a focus on point-of-departure and population variability; and (3) Develop cheminformatics-based, as well as enhanced chemical-biological, models of in vivo reproductive and developmental toxicity that rely on concomitant exploration of chemical descriptors and population-based screening data.
Estado | Finalizado |
---|---|
Fecha de inicio/Fecha fin | 1/7/12 → 30/6/17 |
Enlaces | https://cfpub.epa.gov/ncer_abstracts/index.cfm/fuseaction/display.abstractDetail/abstract_id/9731/report/0 |
Financiación
- U.S. Environmental Protection Agency: USD1,200,000.00
!!!ASJC Scopus Subject Areas
- Seguridad, riesgos, fiabilidad y calidad
- Toxicología
- Ciencias ambientales (todo)
Huella digital
Explore los temas de investigación que se abordan en este proyecto. Estas etiquetas se generan con base en las adjudicaciones/concesiones subyacentes. Juntos, forma una huella digital única.