Bringing clonal haematopoiesis (CHIP) to the clinic through screening, risk profiling and treatment

CHIP is a disease of aging blood cells found in ≫ 1 million Australians associated with age-related diseases including cancer. Using samples from a randomised study of aspirin in the elderly, this project will build a case for screening for CHIP to identify individuals with high levels of CHIP that will benefit from aspirin to prevent cancer. In those with low levels of CHIP, we will develop a risk scoring system to predict risk of progression and we will find ways of preventing growth of CHIP.