UNC Kenan-Flagler

Resultados de la búsqueda

• Terminado

  Determining the role of Tet1 in intestinal stem cell differentiation and self-renewal

  Gracz, A. D. (Investigador principal)

  1/8/19 → 31/7/21

  Proyecto: Investigación

  • Intestinal Stem Cells 100%
  • Ten-eleven Translocation 1 (TET1) 100%
  • Self-renewal 100%
  • Stem Cell Differentiation 100%
  • Stem Cell 100%

• Bacteria as biosensors of marine carbon and energy flow: Quantitative links between substrates, transcriptomics, and metabolism

  Gifford, S. S. M. (Investigador principal)

  National Science Foundation

  1/8/19 → 31/7/23

  Proyecto: Investigación

  • Carbon Flow 100%
  • Dissolved Organic Carbon 100%
  • Microbial Metabolism 100%
  • Bacterial Metabolism 75%
  • Transcriptomics 50%

• Molecular mechanisms of DNA mismatch repair initiation

  Weninger, K. K. R. (Investigador principal)

  National Institute of General Medical Sciences

  25/7/19 → 31/5/23

  Proyecto: Investigación

  • Mismatch Repair 80%
  • Molecular Mechanism 80%
  • DNA Mismatch Repair 80%
  • Mismatch DNA Repair 80%
  • Tethered Particle Motion 37%

• A Sepsis Transition Program to Reduce Morbidity and Mortality in High Risk Individuals

  Kowalkowski, M. M. (CoPI) & Taylor, S. S. P. (CoPI)

  National Institute of Nursing Research

  23/7/19 → 30/4/24

  Proyecto: Investigación

  • Sepsis 100%
  • Post-sepsis 58%
  • Transition Program 50%
  • Sepsis Care 50%
  • High-risk Individuals 50%

• Mechanisms of Nuclear Body Formation in the Early Embryo

  Rieder, L. E. (Investigador principal)

  National Institute of Child Health and Human Development

  18/7/19 → 30/6/22

  Proyecto: Investigación

  • Nuclear Bodies 100%
  • Early Embryo 100%
  • Histone 100%
  • Adaptor 87%
  • Histone Locus Body 75%

• SHF: Small: Collaborative Research: A Parallel Graph-Based Paradigm for HPC Parallel File System Checkers

  Dai, D. D. (Investigador principal)

  National Science Foundation

  15/7/19 → 30/6/23

  Proyecto: Investigación

  • Parallel File System 100%
  • High-Performance Computing 100%
  • High Performance Computing 50%
  • Graph-based 50%
  • Collaborative Research 50%

• Collaborative Research: Dynamical Tides in Close Stellar Binaries and Exoplanetary Systems

  Arras, P. P. L. (Investigador principal)

  National Science Foundation

  15/7/19 → 30/6/23

  Proyecto: Investigación

  • Exoplanet Systems 100%
  • Dynamical Tides 100%
  • Massachusetts Institute of Technology 100%
  • Collaborative Research 100%
  • Binary System 100%

• Collaborative Research: Dynamical Tides in Close Stellar Binaries and Exoplanetary Systems

  Weinberg, N. N. (Investigador principal)

  National Science Foundation

  15/7/19 → 31/10/20

  Proyecto: Investigación

  • Exoplanet Systems 100%
  • Dynamical Tides 100%
  • Massachusetts Institute of Technology 100%
  • Collaborative Research 100%
  • Binary System 100%

• Microglia ontogeny, proliferation and maturation in Alzheimer's Disease

  Garden, G. A. (Investigador principal)

  15/7/19 → 30/6/21

  Proyecto: Investigación

  • Alzheimer's Disease 100%
  • Maturation 100%
  • Ontogeny 100%
  • Microglia 100%
  • Central Nervous System 50%

• Pharmacology of intrathecal/intraventricular polymyxins: A systems-based approach

  Rao, G. G. G. (CoPI), Velkov, T. T. (CoPI), Rao, G. G. G. (Investigador principal) & Kaye, K. K. S. (CoPI)

  8/7/19 → 30/6/24

  Proyecto: Investigación

  • Polymyxin 100%
  • Intraventricular 100%
  • Intrathecal 100%
  • Systems-based Approach 100%
  • Pharmacology 100%

• ENHANCING THE WGS BASED SURVEILLANCE OF SALMONELLA, LISTERIA, STEC AND OTHER FOODBORNE RELATED BACTERIAL PATHOGENS ISOLATED FROM FOOD AND ENVIRONMENT AT THE NATIONAL AND GLOBAL LEVEL

  Thakur, S. S. (Investigador principal) & Cray, P. P. (CoPI)

  U.S. Food and Drug Administration

  5/7/19 → 30/6/20

  Proyecto: Investigación

  • Foodborne Disease 100%
  • Slant Total Electron Content (sTEC) 100%
  • Whole Genome Sequencing 100%
  • Global Level 100%
  • Bacterial Pathogens 100%

• Developing a Cohort of Newly HIV-Diagnosed Persons to Improve Longitudinal Understanding of HIV Care Engagement

  Powers, K. (Investigador principal)

  National Institute of Nursing Research

  5/7/19 → 30/6/21

  Proyecto: Investigación

  • HIV Care Engagement 100%
  • Human Immunodeficiency Virus 100%
  • Care Engagement 50%
  • Transmission Risk 50%
  • People Living with HIV (PLHIV) 33%

• Collaborative Research: How does it end? Exploring thrust terminations of an intra-continental strike-slip fault, north Tibet

  Haproff, P. P. J. (Investigador principal)

  National Science Foundation

  1/7/19 → 30/6/23

  Proyecto: Investigación

  • Continental Strike-slip Faults 100%
  • Haiyuan Fault 100%
  • Intra-continental 100%
  • North Tibet 100%
  • Strike-slip Fault 100%

• CAREER: Biochar Systems for Sustainable Applications in the Food-Energy-Water Nexus

  Yao, Y. Y. (Investigador principal)

  National Science Foundation

  1/7/19 → 31/7/20

  Proyecto: Investigación

  • Biochar Application 100%
  • Biochar System 100%
  • Sustainable Application 100%
  • Biochar 100%
  • Water-Energy Nexus 100%

• From Quantum Entanglement to Tensor Decomposition by Global Optimization

  Chu, M. M. T. (Investigador principal)

  National Science Foundation

  1/7/19 → 30/6/23

  Proyecto: Investigación

  • Entanglement 100%
  • Global Optimization 100%
  • Quantum Entanglement 100%
  • Separability 55%
  • Separable States 50%

• RAPID: Collaborative Research: Building Digital Infrastructure and Communities to Assess Risk of Drinking Water Hazards Caused by Hurricanes

  Bandaragoda, C. C. (Investigador principal) & Faustman, E. E. M. (CoPI)

  National Science Foundation

  1/7/19 → 30/6/21

  Proyecto: Investigación

  • Digital Infrastructure 100%
  • Drinking Water 100%
  • Collaborative Research 100%
  • Water Hazard 100%
  • Research Building 100%

• Collaborative Research: Emergence and Evolution of a Colonial Economy

  Pavao-zuckerman, B. B. (Investigador principal)

  National Science Foundation

  1/7/19 → 31/12/22

  Proyecto: Investigación

  • Colonial Economy 100%
  • Collaborative Research 100%
  • Charleston 100%
  • Urban 100%
  • University of Georgia 80%

• CAREER: Microbial controls on wetland carbon stabilization and storage

  Peralta, A. A. L. (Investigador principal)

  National Science Foundation

  1/7/19 → 30/6/24

  Proyecto: Investigación

  • Wetland Carbon 100%
  • Carbon Stabilization 100%
  • Microbial Control 100%
  • Carbon Storage 100%
  • Wetlands 100%

• Collaborative Research: Emergence and Evolution of a Colonial Economy

  Hadden, C. C. (Investigador principal), Reitz, E. (CoPI) & Reitsema, L. L. (CoPI)

  National Science Foundation

  1/7/19 → 30/6/22

  Proyecto: Investigación

  • Colonial Economy 100%
  • Urban 100%
  • Rural 80%
  • Animal Economy 60%
  • Collaborative Research 50%

• NSF Postdoctoral Fellowship in Biology FY 2019: Deciphering CLE Peptide Signaling Pathways in Sunflower (Helianthus annuus)

  Jones, D. D. S. (Investigador principal)

  National Science Foundation

  1/7/19 → 30/6/22

  Proyecto: Investigación

  • CLE Peptide 100%
  • Helianthus Annuus 100%
  • Helianthus annuus 100%
  • Peptide Signaling 50%
  • Postdoctoral Fellowship 50%

• CAREER: Semantic Multi-Task Learning for Generalizable and Interpretable Language Generation

  Bansal, M. M. (Investigador principal)

  National Science Foundation

  1/7/19 → 30/6/24

  Proyecto: Investigación

  • Language Generation 100%
  • Natural Language Generation 100%
  • Generation Language 100%
  • Multi-task Learning 50%
  • Generation Model 37%

• Estimating Probabilities of Rare Events in Interacting Particle Systems

  Budhiraja, A. A. (Investigador principal)

  National Science Foundation

  1/7/19 → 30/6/23

  Proyecto: Investigación

  • Particle System 100%
  • Reaction-Diffusion System 80%
  • Large Deviation Problem 75%
  • Stochastic Control 75%
  • Interacting Particle Systems 50%

• 2019 Kern Lipid Conference

  Eckel, R. H. (Investigador principal)

  National Institute of Diabetes and Digestive and Kidney Diseases

  1/7/19 → 30/6/20

  Proyecto: Investigación

  • Disease 100%
  • Disease Mechanisms 33%
  • Young Investigators 33%
  • Metabolic 33%
  • Cardiometabolic Disease 33%

• I-Corps: Microalgae Building Enclosures

  Lu, F. (CoPI), Kim, K. (Investigador principal) & Wu, C. (CoPI)

  National Science Foundation

  15/6/19 → 30/11/20

  Proyecto: Investigación

  • Microalgae 100%
  • Building Enclosure 100%
  • Photobioreactor 100%
  • Daylighting 50%
  • Metal Frame 50%

• I-Corps: Adaptable Solar Window

  Zhang, C. D. (Investigador principal)

  National Science Foundation

  15/6/19 → 30/11/20

  Proyecto: Investigación

  • Solar Window 100%
  • Organic Solar Cells 100%
  • Solar Energy Production 66%
  • Solar Energy 66%
  • Photovoltaic System 50%

• Gene-Environment Interactions Causing Differential Susceptibility to Chemical Exposure in High-Throughput Screening

  Reif, D. M. (Investigador principal)

  National Institute of Environmental Health Sciences

  15/6/19 → 31/5/21

  Proyecto: Investigación

  • Differential Susceptibility 100%
  • High Throughput Screening 100%
  • High-Throughput Screening 100%
  • Genetic Variation 66%
  • High-throughput Screening 50%

• Towards comprehensive multiphase flow modelling for nuclear reactor thermal hydraulics

  Colombo, M. M. (Investigador principal)

  Engineering and Physical Sciences Research Council

  1/6/19 → 31/5/22

  Proyecto: Investigación

  • Multiphase Flow Simulation 100%
  • Gas-liquid Flow 100%
  • Liquid Gas 66%
  • Nuclear Reactor 50%
  • Thermal-hydraulic Design 40%

• Three-dimensional organoid culture using the CellRaft microwell technology

  Gebhart, S. C. (Investigador principal)

  National Institute of General Medical Sciences

  1/6/19 → 31/12/20

  Proyecto: Investigación

  • Organoid 100%
  • Organoids 50%
  • Three-dimensional Organoid Culture 50%
  • Microwell 50%
  • Organoid Culture 25%

• Catalyst Award: Plant and Rhizosphere Processes that Prevent Groundwater Contamination from Metals and Nitrates

  Aryal, N. N. (Investigador principal)

  National Science Foundation

  1/6/19 → 31/5/23

  Proyecto: Investigación

  • Nitrate 100%
  • Rhizosphere Processes 100%
  • Groundwater Contamination 100%
  • Plant Processes 100%
  • Provide Support 100%

• Photoacoustic-imaging-guided intravascular sonothrombolysis

  Jiang, X. (Investigador principal) & Yao, J. (CoPI)

  National Institute of Biomedical Imaging and Bioengineering

  1/6/19 → 31/3/21

  Proyecto: Investigación

  • Photoacoustic Imaging 100%
  • Imaging-guided 100%
  • Intravascular Sonothrombolysis 100%
  • Fiber Optics 100%
  • Thrombolysis 80%

• Neurocomputational mechanisms of impaired social decision-making in borderline personality

  Hallquist, M. N. (CoPI)

  1/6/19 → 31/3/24

  Proyecto: Investigación

  • Neurocomputational Mechanism 100%
  • Social Decision-making 100%
  • Borderline Personality Disorder 100%
  • Decision-Making 100%
  • Cingulo-opercular Network 44%

• Optimizing impedance control of an ankle exoskeleton to improve post-stroke walking mechanics and energetics

  Mccain, E. (Investigador principal)

  National Institute of Child Health and Human Development

  15/5/19 → 14/5/22

  Proyecto: Investigación

  • Walking Energetics 100%
  • Walking Mechanics 100%
  • Impedance Control 100%
  • Muscle Weakness 100%
  • Ankle Power 100%

• Defining and Modeling the Response of a Low Gradient Coastal System to Rapid Sea-Level Rise during the Late Pleistocene

  Mallinson, D. D. J. (Investigador principal), Culver, S. S. (CoPI), Dewitt, R. R. (CoPI) & Leorri, E. E. (CoPI)

  National Science Foundation

  15/5/19 → 30/4/23

  Proyecto: Investigación

  • Rapid Sea-level Rise 100%
  • Low Gradient 100%
  • Highstand 66%
  • Geophysical Data 66%
  • Coastal Systems 50%

• Building Infrastructure for Community Capacity in Accelerating Integrated Care

  Stein, G. G. L. (Investigador principal) & Eddington, K. K. M. (CoPI)

  National Institute of Mental Health

  8/5/19 → 29/2/24

  Proyecto: Investigación

  • Community Capacity 100%
  • Integrated Care 100%
  • Accountable Care Organization 100%
  • Built Infrastructure 75%
  • Mental Health 52%

• MICROFABRICATED INSTRUMENTATION TO MEASURE SPHINGOLIPID SIGNALING IN HUMAN ACUTE MYELOID LEUKEMIA

  Allbritton, N. L. (CoPI), Armistead, P. M. (CoPI), Gomez, S. M. (CoPI), Zhang, Q. (CoPI), Allbritton, N. N. L. (Investigador principal), Armistead, P. P. M. (CoPI), Zhang, Q. Q. (CoPI) & Gomez, S. S. (CoPI)

  7/5/19 → 30/4/24

  Proyecto: Investigación

  • Sphingolipid Signaling 100%
  • Acute Myeloid Leukemia Cells 100%
  • Acute Myeloid Leukemia 100%
  • Micro-fabricated 100%
  • Microfabricated Device 66%

• CAREER: Muscle-Inspired Load-Adaptive Actuation for Compliant Robotics

  Bryant, M. M. J. (Investigador principal)

  National Science Foundation

  1/5/19 → 30/4/24

  Proyecto: Investigación

  • Load Adaptive 100%
  • Compliant Robot 100%
  • Muscle-inspired 100%
  • Muscle Tissue 75%
  • Actuator 50%

• NSF INSTRUMENTATION CY19 DEERING

  Deering, T. T. W. (Investigador principal)

  National Science Foundation

  1/5/19 → 30/9/20

  Proyecto: Investigación

  • Review Criteria 100%
  • Research Vessel 100%
  • Oceanographic Instrumentation 100%
  • Shared Use 100%
  • Sailing Schedule 100%

• CAREER: Stochastic Forward and Inverse Problems Involving Dynamical Systems

  Mcgoff, K. K. (Investigador principal)

  National Science Foundation

  1/5/19 → 30/4/24

  Proyecto: Investigación

  • Forward Problem 100%
  • Dynamical Systems 50%
  • Inverse Problem 50%
  • Stochastics 50%
  • Dynamical System 50%

• Rational Oncolytic Virotherapy For Pancreatic Cancer Using Vesicular Stomatitis Virus

  Grdzelishvili, V. Z. (Investigador principal)

  National Cancer Institute

  1/5/19 → 30/4/22

  Proyecto: Investigación

  • Vesicular Stomatitis Virus 100%
  • Pancreatic Cancer 100%
  • Oncolytic Virotherapy 100%
  • Vesiculovirus 100%
  • Virotherapy 100%

• A Global Syphilis Vaccine Targeting Outer Membrane Proteins of Treponema pallidum.

  Radolf, J. J. D. (Investigador principal), Moody, M. M. A. (CoPI), Parr, J. B. (CoPI) & Salazar, J. C. (CoPI)

  National Institute of Allergy and Infectious Diseases

  1/5/19 → 30/4/24

  Proyecto: Investigación

  • Outer Membrane Protein 100%
  • Syphilis 100%
  • Treponema pallidum 100%
  • Vaccine Efficacy 100%
  • Outer Membrane 100%

• University of North Carolina - Chlamydia Vaccine Initiative (UNC-CVI)

  Darville, T. (Investigador principal), Goonetilleke, N. (CoPI) & O'connell, C. M. (CoPI)

  National Institute of Allergy and Infectious Diseases

  1/5/19 → 30/4/24

  Proyecto: Investigación

  • Chlamydia Vaccine 100%
  • Chlamydiae 100%
  • Mouse 83%
  • University of North Carolina 75%
  • Guinea pig 66%

• System toxicological approaches to define and predict thetoxicityofPerand Polyfluoroalkyl Substances

  Tanguay, R. L. R. L. (Investigador principal), Field, J. J. (CoPI), Reif, D. M. (CoPI), Truong, L. L. (CoPI), Ng, C. C. (CoPI) & Dewitt, J. J. (CoPI)

  U.S. Environmental Protection Agency

  1/5/19 → 30/4/23

  Proyecto: Investigación

  • PFAS Mixture 100%
  • Zebra Fish 100%
  • Mouse 100%
  • Antigen-specific Antibody 50%
  • Natural Killer Cell Cytotoxicity 50%

• The immune contexture of colorectal adenomas and serrated polyps

  Wallace, K. K. (Investigador principal), Barry, E. L. (CoPI), Crockett, S. D. (CoPI), Shrubsole, M. J. (CoPI) & Baron, J. A. (CoPI)

  9/4/19 → 31/8/24

  Proyecto: Investigación

  • Immune Contexture 100%
  • Serrated Polyps 100%
  • Immune Response 100%
  • Colorectal Adenoma 100%
  • Precursor 100%

• Commercialization of Enzyme Modified Carbon-Fiber Electrodes Paired with Voltammetry for Simultaneous Real-Time Monitoring of Electroactive and Non-Electroactive Species at Discrete Brain Locations

  Johnson, D. A. (Investigador principal) & Sombers, L. A. (CoPI)

  National Institute of Mental Health

  1/4/19 → 31/3/21

  Proyecto: Investigación

  • Electroactive Species 100%
  • Voltammetry 100%
  • Recording Sites 66%
  • Cyclic Voltammetry 66%
  • In Vivo 66%

• EAGER: An inducible degron system for control of protein degradation in plants.

  Pierce, M. M. (Investigador principal)

  National Science Foundation

  1/4/19 → 31/3/23

  Proyecto: Investigación

  • Degron 100%
  • Protein Degradation 100%
  • Dexamethasone 100%
  • Nicotiana 100%
  • RNA Interference 100%

• Reducing the HIV Reservoir: Next-Generation Latency Reversal Agents and T Cell Population Targets

  Falcinelli, S. S. D. (Investigador principal)

  National Institute of Allergy and Infectious Diseases

  1/4/19 → 31/3/24

  Proyecto: Investigación

  • Latency Reversal Agents 100%
  • T Cell Subpopulations 83%
  • Virus Reservoir 83%
  • AIDS/HIV 83%
  • Cell Population 83%

• CAREER: Robust Decoding of Neural Command for Real Time Human Machine Interactions

  Hu, X. X. (Investigador principal)

  National Science Foundation

  1/4/19 → 31/3/24

  Proyecto: Investigación

  • Human-Computer Interaction 100%
  • Neural Drive 71%
  • Neural Decoding 57%
  • High-density Surface Electromyography 57%
  • Human-machine Interaction 50%

• SPROUT-CTSA Collaborative Telehealth Research Network

  Chuo, J. J. (CoPI), Mcswain, S. D. (CoPI), Olson, C. A. (CoPI), Mcswain, S. S. D. (Investigador principal), Joyner, B. B. (CoPI) & Olson, C. C. A. (CoPI)

  National Center for Advancing Translational Sciences

  1/4/19 → 31/3/24

  Proyecto: Investigación

  • Telehealth 100%
  • American Academy of Pediatrics 9%
  • Telehealth Services 9%
  • Multicenter Research 6%

• UNC MACS/WIHS Combined Cohort Study Clinical Research Site

  Adimora, A. A. (Investigador principal) & Floris-moore, M. M. (CoPI)

  National Heart, Lung, and Blood Institute

  1/4/19 → 31/3/24

  Proyecto: Investigación

  • Combined Cohort 100%
  • Multicenter AIDS Cohort Study 100%
  • Clinical Research 90%
  • Cohort Analysis 90%
  • Human Immunodeficiency Virus 64%

• Harnessing Platelet-Endothelial Interactions for Exosome Delivery

  Cheng, K. K. (Investigador principal) & Cheng, K. (CoPI)

  1/4/19 → 31/7/24

  Proyecto: Investigación

  • Exosomal Delivery 100%
  • Exosomes 100%
  • Platelet 100%
  • Exosome 100%
  • Injured Tissue 57%