UNC Kenan-Flagler

Resultados de la búsqueda

• Terminado

  Drug-use associated infective endocarditis: Post-hospitalization outcomes and patient treatment preferences

  Schranz, A. J. (Investigador principal)

  National Institute on Drug Abuse

  1/4/20 → 31/3/24

  Proyecto: Investigación

  • Drug Use 100%
  • Patient Treatment Preferences 100%
  • Infective Endocarditis 100%
  • Bacterial Endocarditis 100%
  • Disease 43%

• Expoitation of ER Stress Induced Immune Dysfunction to Improve Immunotherapy

  Thaxton, J. (CoPI) & Thaxton, J. J. E. (Investigador principal)

  1/4/20 → 31/3/24

  Proyecto: Investigación

  • T Cells 100%
  • Immune Dysfunction 100%
  • Stress-induced 100%
  • Endoplasmic Reticulum Stress (ER stress) 100%
  • Endoplasmic Reticulum Stress 100%

• Molecular profiling of medullary descending pain modulation circuits to discover novel analgesic targets

  Scherrer, G. (CoPI)

  1/4/20 → 30/6/20

  Proyecto: Investigación

  • Modulation Circuit 100%
  • Rostral Ventrolateral Medulla 100%
  • Descending Pain Modulation 100%
  • Novel Analgesics 100%
  • Rostral Ventromedial Medulla 100%

• A novel diabetic co-infection model to study pathogen interaction during co-infection

  Thurlow, L. R. (CoPI)

  19/3/20 → 28/2/21

  Proyecto: Investigación

  • Co-infection 100%
  • Diabetic 100%
  • Pathogen Interaction 100%
  • Staphylococcus Aureus 100%
  • Co-infection Model 100%

• AIM BACK UH3 Transition

  George, S. Z. (Investigador principal)

  National Center for Complementary and Integrative Health

  18/3/20 → 29/2/24

  Proyecto: Investigación

  • Care Pathway 100%
  • Healthcare Management 100%
  • Pain Interference 75%
  • Integrated Care Pathways 75%
  • Modal 75%

• Molecular Biotechnology Laboratory Education Modules (MBLEM)

  Kelly, R. R. M. (Investigador principal) & Goller, C. C. C. (CoPI)

  National Institute of General Medical Sciences

  15/3/20 → 29/2/24

  Proyecto: Investigación

  • Laboratory Education 100%
  • Molecular Biology 100%
  • Education Module 75%
  • Molecular Biotechnology 75%
  • USA 75%

• Collaborative Research: Tracing Coal Ash Solids in the Environment - Implications for long-term contamination of the aquatic ecosystem

  Vengosh, A. A. (Investigador principal)

  National Science Foundation

  1/3/20 → 28/2/23

  Proyecto: Investigación

  • Aquatic Ecosystem 100%
  • North Carolina 100%
  • Coal Ash 100%
  • Aquatic Ecosystems 100%
  • Collaborative Research 100%

• Collaborative Research: Tracing Coal Ash Solids in the Environment - Implications for long-term contamination of the aquatic ecosystem

  Cowan, E. E. A. (Investigador principal) & Brachfeld, S. S. A. (CoPI)

  National Science Foundation

  1/3/20 → 28/2/23

  Proyecto: Investigación

  • Long-term Contamination 100%
  • Aquatic Ecosystem 50%
  • North Carolina 50%
  • Coal Ash 50%
  • Aquatic Ecosystems 50%

• Center for Environmental and Health Effects of PFAS

  Mattingly, C. J. (Investigador principal), Knappe, D. D. R. (CoPI), Griffith, E. E. H. (CoPI), Baker, E. E. M. (CoPI), Baker, E. E. S. (CoPI), Hoppin, J. J. (CoPI), Knappe, D. R. (CoPI), Kullman, S. W. (CoPI), May, K. (CoPI), Muddiman, D. C. (CoPI), Planchart, A. J. (CoPI), Ranjithan, R. R. S. (CoPI) & Reif, D. M. (CoPI)

  National Institute of Environmental Health Sciences

  28/2/20 → 31/1/24

  Proyecto: Investigación

  • North Carolina 100%
  • Public Health 100%
  • Bioaccumulation 86%
  • Environmental Impact 80%
  • Health Effects 80%

• PM exposure and changes in respiratory host defense responses

  Jaspers, I. I. (Investigador principal) & Alexis, N. E. (CoPI)

  National Institute of Environmental Health Sciences

  24/2/20 → 31/8/24

  Proyecto: Investigación

  • PM Exposure 100%
  • Host Resistance 100%
  • Immunocompetent Cell 91%
  • Epithelial Cell 83%
  • China 75%

• Image-guided, ultrasound-enhanced long-term intracranial drug delivery

  Brudno, Y. Y. (Investigador principal) & Dayton, P. A. (CoPI)

  National Cancer Institute

  15/2/20 → 31/1/22

  Proyecto: Investigación

  • Intracranial Drug Delivery 100%
  • Blood Brain Barrier 100%
  • Prodrug 83%
  • Ultrasound-enhanced 66%
  • Image-guided 66%

• The impact of obesity on cerebral glucose transport and metabolism

  Hwang, J. J. J. (Investigador principal)

  7/2/20 → 31/1/24

  Proyecto: Investigación

  • Cerebral Glucose Metabolism 100%
  • Glucose Metabolism 100%
  • Obesity 100%
  • Glucose Transport 100%
  • Metabolic Pathway 100%

• Collaborative Research: Novel neurocognitive assessment of engineering education interventions applied to systems thinking

  Gero, J. J. S. (Investigador principal)

  National Science Foundation

  1/2/20 → 31/1/23

  Proyecto: Investigación

  • Engineering Education 100%
  • Engineering Problem 100%
  • Priming 100%
  • Concept Map 85%
  • Collaborative Research 50%

• Tolerising antigen-specific immunotherapy for type 1 diabetes

  Kuila, D. (Investigador principal), Basha, O. M. (CoPI) & Hamilton-williams, E. E. (Investigador principal)

  National Science Foundation

  1/2/20 → 31/5/21

  Proyecto: Investigación

  • Microreactor 100%
  • Hydrocarbons 100%
  • Specific Immunotherapy 100%
  • High Productivity 100%
  • Type 1 Diabetes Mellitus (T1DM) 100%

• The pig: A novel large animal model of allergic eosinophilic esophagitis

  Kaeser, T. E. (Investigador principal) & Laster, S. M. (CoPI)

  National Institute of Allergy and Infectious Diseases

  1/2/20 → 31/1/22

  Proyecto: Investigación

  • Eosinophilic Esophagitis 100%
  • Large Animal Model 100%
  • Esophagitis 100%
  • Food Allergy 69%
  • Esophagus 20%

• Understanding and Addressing Racial Disparities in Guideline-Indicated Management of Symptomatic Peripheral Artery Disease

  Kalbaugh, C. C. A. (CoPI)

  National Heart, Lung, and Blood Institute

  15/1/20 → 31/12/23

  Proyecto: Investigación

  • Racial Disparity 100%
  • Racial Disparities 60%
  • Peripheral Arterial Disease 60%
  • Surgeon 60%
  • Health Care 50%

• Collaborative Research: ABI Development: Integrated platforms for protein structure and function predictions

  Kc, D. D. B. (Investigador principal)

  National Science Foundation

  7/1/20 → 30/6/21

  Proyecto: Investigación

  • Protein Structure Prediction 100%
  • Collaborative Research 100%
  • Integrated Platform 100%
  • Protein Function 100%
  • Prediction Function 100%

• NSF Convergence Accelerator Track J: Accelerating commercial marine fish production in US: developing sustainable feeds, establishing feed suppliers and enhancing market acceptance

  Watanabe, W. O. (CoPI), Carroll, P. (CoPI) & Alam, M. S. (Investigador principal)

  National Science Foundation

  6/1/20 → 30/11/23

  Proyecto: Investigación

  • Sustainable Feed 100%
  • Market Acceptance 100%
  • Commercial Marine Fish 100%
  • Marine Fish Production 100%
  • Fish Production 100%

• Framework: Sofware: Collaborative Research: CyberWater -An open and sustainable framework for diverse data and model integration with provenance and access to HPC

  Zhang, Y. Y. (Investigador principal)

  National Science Foundation

  1/1/20 → 31/12/23

  Proyecto: Investigación

  • Open Framework 100%
  • Sofware 100%
  • Sustainable Framework 100%
  • Water Research 100%
  • Research Community 100%

• CRCE and Related Activities Core

  Blobe, G. C. (Investigador principal), Blobe, G. G. C. (Investigador principal) & Antonia, S. J. (Investigador principal)

  National Cancer Institute

  1/1/20 → 31/12/23

  Proyecto: Investigación

  • Cancer Research 100%
  • Malignant Neoplasm 100%
  • Duke University 87%
  • Research Career Development 75%
  • Cancer Institute 62%

• Analytical pipelines for data and model integration: finding informed pathways for antimicrobial resistance control

  Lanzas, C. (Investigador principal)

  National Institute of General Medical Sciences

  1/1/20 → 31/12/23

  Proyecto: Investigación

  • Pathogen 100%
  • Antibiotic Resistance 100%
  • Infectious Agent 100%
  • Antimicrobial Resistance 100%
  • Pathogen Interaction 66%

• Role of Ankyrin-B in the Nervous System

  Lorenzo, D. N. (CoPI) & Lorenzo, D. D. N. (Investigador principal)

  1/1/20 → 31/12/23

  Proyecto: Investigación

  • Ankyrin 100%
  • Nervous System 100%
  • Synaptogenesis 44%
  • Central Nervous System 33%
  • Axonal Growth 22%

• Manipulation of MHC expression using TGF-beta2 to reduce mesenchymal stem cell immunogenicity

  Berglund, A. K. (Investigador principal)

  NIH Office of the Director

  15/12/19 → 30/11/23

  Proyecto: Investigación

  • Transforming Growth Factor Beta2 100%
  • Major Histocompatibility Complex 80%
  • Immunogenicity 80%
  • Mesenchymal Stem Cell 80%
  • Complex Expressions 60%

• Correction of endocrine disruptor-induced transgenerational epimutations by CRISPR-dCas9

  Bhandari, R. K. (Investigador principal)

  National Institute of Child Health and Human Development

  15/12/19 → 30/11/21

  Proyecto: Investigación

  • Transgenerational 100%
  • Epimutation 100%
  • Endocrine Disruptors 100%
  • CRISPR-dCas9 100%
  • CRISPR 50%

• Cell-Mediated Targeted Redox Intervention for the Treatment and Prevention of Atherosclerosis

  Bahnson, E. E. M. (Investigador principal)

  National Heart, Lung, and Blood Institute

  15/12/19 → 30/11/23

  Proyecto: Investigación

  • Redox 100%
  • Atherosclerosis 100%
  • Nrf2 Activator 90%
  • Transcription Factor Nrf2 80%
  • Macrophages 70%

• Identification of a central player in neoplastic transformation of intestinal stem cells:protocadherin 8

  Van Landeghem, L. L. C. (Investigador principal)

  National Cancer Institute

  10/12/19 → 30/11/21

  Proyecto: Investigación

  • Protocadherin-8 100%
  • Intestinal Stem Cells 66%
  • Neoplastic Transformation 66%
  • Stem Cell 66%
  • Intestinal Stem Cell 66%

• Identifying structural differences between fibrinogen and fibrin to provide novel therapeutic targets

  Offenbacher, A. (Investigador principal)

  National Heart, Lung, and Blood Institute

  1/12/19 → 30/11/22

  Proyecto: Investigación

  • Novel Therapeutic Targets 100%
  • Fibrinogen 100%
  • Structural Difference 100%
  • Fibrin 100%
  • Hydrogen/Deuterium Exchange Mass Spectrometry 23%

• Jim Crow in the Asylum: Psychiatry and Civil Rights in the American South

  Smith, K. K. (Investigador principal)

  U.S. National Library of Medicine

  1/12/19 → 30/11/22

  Proyecto: Investigación

  • American South 100%
  • Jim Crow 100%
  • Civil Rights 100%
  • Asylum 100%
  • Mental Health 100%

• TAK1 Inhibition by (5Z)-7-Oxozeaenol Analogues for Anticancer Leads

  Croatt, M. P. (Investigador principal)

  National Cancer Institute

  1/12/19 → 30/11/22

  Proyecto: Investigación

  • Anticancer 100%
  • Kinase 100%
  • Cancer Cell 100%
  • High-Performance Liquid Chromatography 100%
  • IC50 100%

• Uncovering the Mechanisms of PFAS-induced Immunotoxicity

  Kullman, S. W. (Investigador principal) & Kullman, S. S. W. (Investigador principal)

  National Institute of Environmental Health Sciences

  1/12/19 → 31/1/24

  Proyecto: Investigación

  • Substance-induced 100%
  • Immunotoxicity 100%
  • Polyfluoroalkyl Substances 75%
  • Perfluorooctanesulfonic Acid 32%
  • Health Hazard 22%

• EAGER: Lambda-Red-enhanced homologous recombination in plants

  Alonso, J. J. M. (Investigador principal) & Stepanova, A. A. N. (CoPI)

  National Science Foundation

  1/12/19 → 30/11/23

  Proyecto: Investigación

  • Red-Enhanced 100%
  • Lambda Red 100%
  • Genome Editing 100%
  • Repair Template 50%
  • Homologous Recombination 50%

• Computational and experimental insights into the structure and dynamics of heterochromatin

  Kireev, D. D. (CoPI) & Hathaway, N. N. A. (CoPI)

  1/12/19 → 30/11/23

  Proyecto: Investigación

  • Heterochromatin 100%
  • Chromatin 100%
  • Dynamics 100%
  • Octamer-binding Transcription Factor 4 (OCT4) 85%
  • In Vivo Assay 57%

• Optimal Use of Grid-Connected Energy Storage to Reduce Human Health Impacts

  Johnson, J. J. (Investigador principal), Garcia Menendez, F. F. G. (CoPI), Fell, H. H. (CoPI) & Morrill, M. M. S. (CoPI)

  National Science Foundation

  15/11/19 → 31/10/23

  Proyecto: Investigación

  • Grid-connected 100%
  • Energy Storage 100%
  • Sectoral Emissions 50%
  • Health Impact 50%
  • Power Sector 50%

• SHF:Small:Collaborative Research: Application-aware Energy Modeling and Power Management for Parallel and High Performance Computing

  Yan, Y. Y. (Investigador principal)

  National Science Foundation

  15/10/19 → 30/9/20

  Proyecto: Investigación

  • Application-aware 100%
  • Energy Modeling 100%
  • Power Energy 50%
  • Power Management 50%
  • Collaborative Research 50%

• CPS: Small: Worker-in-the-loop real time safety system for short-duration highway workzones

  Tabkhi, H. (Investigador principal) & Shoghli, O. O. (CoPI)

  National Science Foundation

  1/10/19 → 30/9/23

  Proyecto: Investigación

  • Real-time Safety 100%
  • System Safety 100%
  • Highway Work Zone 66%
  • Safety System 50%
  • Human-in-the-loop 50%

• RI: Small: Principles of Normative Multiagent Systems for Decentralized Applications

  Singh, M. M. P. (Investigador principal)

  National Science Foundation

  1/10/19 → 30/9/23

  Proyecto: Investigación

  • Decentralized Applications 100%
  • Normative multi-agent Systems 100%
  • Multi Agent Systems 100%
  • Multi-agent Systems 50%
  • Interoperation 50%

• Integrating Human Wearers' Perception and Cognition into Prosthesis Control Policy

  Huang, H. H. (Investigador principal) & Feng, J. J. (CoPI)

  National Science Foundation

  1/10/19 → 30/9/23

  Proyecto: Investigación

  • Control Policy 100%
  • Control Parameter 100%
  • Tuning Procedure 55%
  • Wearer 50%
  • Prosthesis Control 50%

• Green and Sustainable Water Purification Membranes

  Poler, J. C. J. C. (Investigador principal), Sahu, A. A. (CoPI), Rollins, R. R. (CoPI), Jones, A. A. (CoPI), Oliver, S. S. (CoPI) & Reid, C. C. (CoPI)

  U.S. Environmental Protection Agency

  1/10/19 → 30/9/21

  Proyecto: Investigación

  • Sustainable Water Purification 100%
  • Water Purification Membrane 100%
  • Cellulose Nanofibers 100%
  • Polyfluoroalkylated 100%
  • Potable Water 100%

• SHF: Small: Collaborative Research: Efficient Memory Persistency for GPUs

  Zhou, H. H. (Investigador principal)

  National Science Foundation

  1/10/19 → 30/9/23

  Proyecto: Investigación

  • Memory Persistence 100%
  • Main Memory 100%
  • Persistency Models 80%
  • Persistent Memory 80%
  • Graphics Processing Unit 80%

• SHF: Small: A Hybrid NVM based Computing Architecture for Machine Learning Applications

  Dai, D. D. (Investigador principal), Cheng, D. D. (CoPI) & Wang, Y. Y. (CoPI)

  National Science Foundation

  1/10/19 → 30/9/23

  Proyecto: Investigación

  • Nonvolatile Memory Technologies 100%
  • Machine Learning Applications 50%
  • Technology-based 50%
  • Memory Intensive Computing 50%
  • Computing Architecture 50%

• CAREER: Programming the Existing and Emerging Memory Systems for Extreme-scale Parallel Performance

  Yan, Y. Y. (Investigador principal)

  National Science Foundation

  1/10/19 → 31/1/23

  Proyecto: Investigación

  • Memory Systems 100%
  • Extreme Scale 100%
  • Parallel Performance 100%
  • Emerging Memory 100%
  • Memory System 100%

• RI: Small: Information-theoretic Multiagent Paths for Anticipatory Control of Tasks (IMPACT)

  Pandey, V. (Investigador principal)

  National Science Foundation

  1/10/19 → 30/9/23

  Proyecto: Investigación

  • Multiagents 100%
  • Robot 100%
  • Tasks 100%
  • Information Gain 100%
  • multi-agent 100%

• DIVERSIFYING TREE HOST RANGE FOR SUSTAINABLE PRODUCTION OF BIANCHETTO TRUFFLES- TUBER BORCHII

  Isikhuemhen, O. S. O. M. S. (Investigador principal)

  National Institute of Food and Agriculture

  1/10/19 → 30/9/22

  Proyecto: Investigación

  • Truffle 100%
  • Truffles 100%
  • Bianchetto Truffle 50%
  • Tuber Borchii 50%
  • Host Range 50%

• CHARACTERIZING AND IMPROVING HUMANIZED IMMUNE SYSTEM MOUSE MODELS (IMM-HIS)

  Garcia-martinez, V. J. (Investigador principal)

  1/10/19 → 30/9/20

  Proyecto: Investigación

  • Mouse Model 100%
  • Immune System 100%
  • Neonatal Tissues 50%
  • University of North Carolina 50%
  • Infectious Diseases 50%

• Characterization of interferon-lambda 1 as a treatment for COVID-19

  Tyrrell, D. L. J. (Investigador principal), Feld, J. J. J. J. (CoPI), Gehring, A. J. A. J. (CoPI) & Santer, D. D. (CoPI)

  1/10/19 → 31/3/22

  Proyecto: Investigación

  • COVID-19 100%
  • Interferon lambda (IFN-λ) 100%
  • Interleukin 29 100%
  • COVID-19 Patients 57%
  • Virus 57%

• cGAS-mediated glial responses to DNA damage: A pilot study

  Richardson, C. A. (Investigador principal)

  National Institute of Neurological Disorders and Stroke

  30/9/19 → 31/8/21

  Proyecto: Investigación

  • Cyclic GMP-AMP Synthase (cGAS) 100%
  • Adenosine Monophosphate 100%
  • DNA Damage Response 100%
  • Cyclic Guanosine Monophosphate 100%
  • Synthetase 100%

• Re-engineering Postnatal Unit Care and the Transition Home to Reduce Perinatal Morbidity and Mortality

  Stuebe, A. A. M. (Investigador principal)

  Agency for Healthcare Research and Quality

  30/9/19 → 29/9/23

  Proyecto: Investigación

  • Perinatal Mortality 100%
  • Perinatal Morbidity 100%
  • Postnatal Care 100%
  • Mother-infant 66%
  • Neonatal Morbidity 50%

• Re-engineering Postnatal Unit Care and the Transition Home to Reduce Perinatal Morbidity and Mortality

  Stuebe, A. A. M. (Investigador principal)

  Agency for Healthcare Research and Quality

  30/9/19 → 29/9/23

  Proyecto: Investigación

  • Neonatal Morbidity 100%
  • Perinatal Mortality 100%
  • Transition Home 100%
  • Antenatal Care 100%
  • Perinatal Morbidity 100%

• Group-based mindfulness for patients with chronic low back pain in the primary care setting

  Morone, N. N. E. (Investigador principal)

  National Center for Complementary and Integrative Health

  28/9/19 → 31/8/20

  Proyecto: Investigación

  • Chronic Low Back Pain (cLBP) 100%
  • Mindfulness 100%
  • Group-based 100%
  • Primary Care Setting 100%
  • Low Back Pain 100%

• Non-toxic, nature-inspired perfusion and high subzero ice-free isochoric technologies for extending heart preservation

  Taylor, M. J. (Investigador principal) & Rubinsky, B. (CoPI)

  National Heart, Lung, and Blood Institute

  24/9/19 → 19/9/21

  Proyecto: Investigación

  • Cryoprotectant 100%
  • Heart Preservation 100%
  • Machine Perfusion 75%
  • Donor Heart 66%
  • Nature-inspired 50%