UNC Kenan-Flagler

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• Terminado

  Developing a yeast system to study virus-host interactions in Mononegavirales

  Grdzelishvili, V. Z. (Investigador principal)

  National Institute of Allergy and Infectious Diseases

  1/6/08 → 31/5/09

  Proyecto: Investigación

  • Yeast System 100%
  • Mononegavirales 100%
  • Virus-host Interactions 100%
  • Virus Cell Interaction 100%
  • Vesicular Stomatitis Virus 66%

• Alveolar Basement Membrane/Cell Interactions in the Lung

  Sannes, P. L. (Investigador principal)

  National Heart, Lung, and Blood Institute

  1/6/08 → 31/3/09

  Proyecto: Investigación

  • AT2 Cells 100%
  • Membrane Cell 100%
  • Basement Membrane 100%
  • Alveolar Cell 66%
  • Lung 50%

• Structure and Inhibition of the Conjugative DNA Relaxase-Helicase

  Redinbo, M. (Investigador principal)

  National Institute of Allergy and Infectious Diseases

  1/6/08 → 31/5/14

  Proyecto: Investigación

  • Conjugative 100%
  • Transfer DNA 100%
  • DNA Transfer 87%
  • TraI 50%
  • Antibiotic-resistant Bacteria 50%

• Alphavirus Modulation of the Host Type I Interferon System

  Cruz, C. (Investigador principal)

  National Institute of Allergy and Infectious Diseases

  1/6/08 → 31/5/10

  Proyecto: Investigación

  • Alphavirus 100%
  • interferon 100%
  • Type I Interferon System 50%
  • Non-structural Protein 25%
  • Virus 18%

• Information Seeking Support Systems (IS3) Workshop

  Marchionini, G. G. J. (Investigador principal)

  National Science Foundation

  1/6/08 → 31/5/09

  Proyecto: Investigación

  • Seeking Support 100%
  • Support System 100%
  • Information Seeking 100%
  • Information Support 100%
  • Exploratory Search 60%

• Understanding Homology in Genetic Recombination

  Singleton, S. F. (Investigador principal)

  National Institute of General Medical Sciences

  1/6/08 → 31/5/09

  Proyecto: Investigación

  • Biological Functions 100%
  • Escherichia coli 100%
  • Infectious Agent 100%
  • Genetic Recombination 100%
  • RecA 100%

• C. elegans Gastrulation: a Model for Understanding Apical Constriction Mechanisms

  Goldstein, R. P. (Investigador principal) & Goldstein, R. P. (CoPI)

  National Institute of General Medical Sciences

  1/6/08 → 31/7/21

  Proyecto: Investigación

  • Gastrulation 100%
  • Apical Constriction 50%
  • Caenorhabditis Elegans 50%
  • Neural Tube 40%
  • Cell Shape 25%

• Genetics of Telomerase in C. elegans

  Ahmed, S. C. (Investigador principal)

  National Institute of General Medical Sciences

  1/6/08 → 31/5/09

  Proyecto: Investigación

  • Telomerase 100%
  • Caenorhabditis Elegans 100%
  • Genetics 100%
  • Telomere 55%
  • Activity in Vivo 33%

• ADVANCED TECHNOLOGY FOR LOW COST ETHANOL FROM ENGINEERED CELLULOSIC BIOMASS

  Jameel, H. H. (Investigador principal), King, J. S. (CoPI), Chiang, V. (CoPI) & Kelley, S. S. (CoPI)

  U.S. Department of Agriculture

  22/5/08 → 31/5/12

  Proyecto: Investigación

  • Cellulosic Biomass 100%
  • Wood 75%
  • Ethanol 50%
  • Pretreatment 50%
  • Growing Season 50%

• UNC Clinical Translation Science Award-T32 Program (TL1)

  Runge, M. M. (Investigador principal), Pisano, E. D. (CoPI) & Watkins, P. B. (CoPI)

  National Center for Research Resources

  19/5/08 → 30/4/12

  Proyecto: Investigación

  • Students 100%
  • Occupational Career 100%
  • Professional Occupations 100%
  • Multidisciplinary Team 50%
  • Scientific Translation 50%

• UNC Clinical and Translational Science Award

  Runge, M. M. (Investigador principal), Pisano, E. D. (CoPI) & Runge, M. (CoPI)

  National Center for Research Resources

  19/5/08 → 30/4/12

  Proyecto: Investigación

  • Pilot Projects 100%
  • Translational Science 92%
  • Clinical Science 92%
  • University of North Carolina 61%
  • Research Design 60%

• The effects of natural selection and recombination on molecular variation in stru

  Schug, M. M. D. (Investigador principal)

  National Institute of Child Health and Human Development

  16/5/08 → 15/5/11

  Proyecto: Investigación

  • Natural Selection 100%
  • Crossing over 66%
  • Genetic Drift 66%
  • Population Structure 50%
  • Natural Recombination 50%

• Etiology of translocations in hematopoietic cells

  Richardson, C. A. (Investigador principal)

  National Cancer Institute

  15/5/08 → 30/10/09

  Proyecto: Investigación

  • Etiology 100%
  • Topoisomerase Inhibitors 100%
  • Hematopoietic Cells 100%
  • Mixed-phenotype Acute Leukemia 100%
  • DNA Gyrase 100%

• Roles for TAK1 in T cell development, function and tumorigenesis

  Wan, Y. (Investigador principal) & Wan, Y. (CoPI)

  National Institute of Allergy and Infectious Diseases

  15/5/08 → 30/4/09

  Proyecto: Investigación

  • T Cells 100%
  • Development Functions 100%
  • T Cell Development 100%
  • Tumorigenesis 100%
  • Transforming Growth Factor Beta 100%

• Early Intervention in a mouse model of NMDA hypofunction

  Moy, S. S. (Investigador principal)

  National Institute of Mental Health

  10/5/08 → 31/3/14

  Proyecto: Investigación

  • N-Methyl-D-Aspartic Acid 100%
  • Dementia Praecox 100%
  • NMDA Hypofunction 50%
  • Mouse Model 50%
  • Schizophrenia 50%

• Functionally Significant Polymorphisms in Serotonin Pathway Genes

  Koller, B. H. (Investigador principal)

  National Institute of Mental Health

  7/5/08 → 30/4/09

  Proyecto: Investigación

  • 5-HTT 100%
  • Polymorphism 100%
  • Serotonin Pathway 100%
  • Obsessive-Compulsive Disorder 50%
  • Serotonin 50%

• T regulatory cell suppression of CD8+ cell responses during FIV Infection

  Fogle, J. (Investigador principal)

  National Institute of Allergy and Infectious Diseases

  1/5/08 → 30/4/13

  Proyecto: Investigación

  • Regulatory T (Treg) Cells 100%
  • Cell Suppression 100%
  • Cell Response 100%
  • CD8+ 100%
  • CD8+ Cell 100%

• A Tetravalent Dengue Vaccine Based on Alphavirus Replicons

  White, L. J. (Investigador principal)

  National Institute of Allergy and Infectious Diseases

  1/5/08 → 30/4/14

  Proyecto: Investigación

  • Tetravalent Dengue Vaccine 100%
  • Maternal Antibodies 100%
  • Live Attenuated Vaccine 66%
  • Maternal Antibody 60%
  • Neutralizing Antibodies 50%

• Disparities in Post-Acute Rehabilitation Care

  Freburger, J. K. (Investigador principal)

  National Institute of Child Health and Human Development

  1/5/08 → 30/4/09

  Proyecto: Investigación

  • Rehabilitation (Therapeutic Procedure) 100%
  • Community Traits 25%
  • Hospital Discharge Records 25%
  • Socioeconomic Disparities 12%
  • Geographic Characteristics 12%

• Functional Neuroimaging of Psychopharmacologic Intervention for Autism

  Dichter, G. S. (Investigador principal)

  National Institute of Mental Health

  8/4/08 → 31/3/14

  Proyecto: Investigación

  • Autism 100%
  • Functional Magnetic Resonance Imaging 100%
  • Neuroimaging 100%
  • Functional Neuroimaging 100%
  • Symptom Expression 42%

• Nikon AZ100 Macro/Micro Zoom Microscope

  Horowitz, J. M. (Investigador principal)

  National Center for Research Resources

  5/4/08 → 31/3/09

  Proyecto: Investigación

  • Human Disease 100%
  • Resolution Image 100%
  • Human Cancer 100%
  • Optical Systems 100%
  • Broad Range 100%

• UNIV. TECHNICAL ASSISTANCE PROJECTS IN SUPPORT OF THE GLOBAL AIDS PROGRAM

  Behets, W.

  Centers for Disease Control and Prevention

  1/4/08 → 31/3/09

  Proyecto: Investigación

• L polymerase domains and mRNA posttranscriptional modifications in Mononegavirale

  Grdzelishvili, V. Z. (Investigador principal)

  National Institute of General Medical Sciences

  1/4/08 → 31/3/11

  Proyecto: Investigación

  • L Protein 100%
  • Mononegavirales 100%
  • Protein L 100%
  • Dihydrolipoamide Dehydrogenase 100%
  • Post-transcriptional Modification 50%

• Genome-wide recombination as a risk factor for nondisjunction

  Hollis, N. D. (Investigador principal)

  National Institute of General Medical Sciences

  1/4/08 → 31/3/09

  Proyecto: Investigación

  • Nondisjunction 100%
  • Risk Factors 50%
  • Recombination 50%
  • Emory University 35%
  • Graduate Student 33%

• Plexin-A1: Regulation by CIITA and Immunologic Function

  Ting, J. P. Y. (Investigador principal)

  National Institute of Allergy and Infectious Diseases

  1/4/08 → 31/3/18

  Proyecto: Investigación

  • CIITA 100%
  • Immunologic Function 100%
  • Semaphorin 53%
  • Dendritic Cell 38%
  • T Lymphocyte Activation 16%

• Intestinal Stem/progenitor Cell Potency and Competence

  Magness, S. T. (Investigador principal)

  National Institute of Diabetes and Digestive and Kidney Diseases

  1/4/08 → 31/3/09

  Proyecto: Investigación

  • Stem Progenitor Cells 100%
  • Cell Potency 100%
  • Cell Competence 100%
  • SRY-box Transcription Factor 9 (SOX9) 80%
  • SOX Family 60%

• SOX2 is a dose-dependent regulator of retinal neural progenitor competence

  Pevny, L. H. (Investigador principal)

  National Eye Institute

  1/4/08 → 31/3/12

  Proyecto: Investigación

  • SOX2 100%
  • Sex-determining Region Y-box 2 (SOX2) 50%
  • Dose Effect 50%
  • Neural Progenitors 50%
  • Retinal Progenitors 37%

• Adrenomedullin Signaling in Vascular Development

  Caron, K. M. (Investigador principal)

  National Heart, Lung, and Blood Institute

  1/4/08 → 31/3/13

  Proyecto: Investigación

  • Lymphangiogenesis 100%
  • Adrenomedullin 70%
  • Vascular Development 70%
  • Lymphatic Vasculature 50%
  • Lymph Duct 50%

• Estuarine air-Sea CO2 Fluxes: Evaluating the Impact of Climatological Drivers Spanning Multiple Temporal Scales using Ships-of-Opportunity and Remote Sensing

  Paerl, H. H. W. (Investigador principal), Hales, B. B. (CoPI) & Wetz, M. M. (CoPI)

  National Science Foundation

  1/4/08 → 31/3/12

  Proyecto: Investigación

  • Opportunistic Sensing 100%
  • Remote Sensing 100%
  • Aquatic Ecosystem 100%
  • North Carolina 100%
  • Air-sea CO2 Flux 50%

• Analysis of Genomic and Proteomic Changes in Glia That Lead To Hydrocephalus

  Mccarthy, K. D. (Investigador principal)

  National Institute of Child Health and Human Development

  1/4/08 → 31/3/09

  Proyecto: Investigación

  • Heart Ventricle Pressure 100%
  • Proteomic Changes 100%
  • Small Molecule 50%
  • Genomic Changes 50%
  • Glia 50%

• SEARCH Nutrition Ancillary Study 2

  Mayer-davis, E. J. (Investigador principal) & The, N. (CoPI)

  National Institute of Diabetes and Digestive and Kidney Diseases

  1/4/08 → 31/8/19

  Proyecto: Investigación

  • Nutrition Status 100%
  • Ancillary 100%
  • Type 1 Diabetes Mellitus (T1DM) 100%
  • Metabolic Status 100%
  • Diabetes Mellitus 100%

• An Investigation of Neuropsychological Endophenotypes in Autism and Fragile X

  Martin, G. E. (Investigador principal) & Losh, M. C. (CoPI)

  National Institute of Mental Health

  1/4/08 → 31/3/09

  Proyecto: Investigación

  • Endophenotype 100%
  • Autism 50%
  • Social Cognition 33%
  • Premutation 33%
  • Genetics 25%

• A Nonhuman Primate Model of Infant CMV Infection

  De Paris, K. K. (Investigador principal) & Abel, K. (CoPI)

  1/4/08 → 31/3/11

  Proyecto: Investigación

  • CMV Infection 100%
  • Human Cytomegalovirus 100%
  • Cytomegalovirus Infection 64%
  • Virus 35%
  • Rhesus CMV 28%

• Recombinant Lactobacillus as an Oral Mucosal Vaccine Against HIV-1

  Dean, G. A. (Investigador principal)

  National Institute of Dental and Craniofacial Research

  20/3/08 → 31/1/14

  Proyecto: Investigación

  • Lactobacillus Gasseri 100%
  • Recombinant Lactobacillus 100%
  • Human Immunodeficiency Virus 1 80%
  • Vaccine Efficacy 80%
  • Vaccine Vector 24%

• Discharge Summary Availability and Discontinuity Errors

  Moore, C. C. (Investigador principal)

  Agency for Healthcare Research and Quality

  17/3/08 → 28/2/09

  Proyecto: Investigación

  • Adverse Events 100%
  • Discharge Summary 100%
  • Hospital Discharge 100%
  • Adverse Event 100%
  • Error Event 66%

• Mechanisms of cytoskeletal crosstalk during cellular motility

  Rogers, S. (Investigador principal)

  National Institute of General Medical Sciences

  15/3/08 → 28/2/13

  Proyecto: Investigación

  • Cell Motility 100%
  • Actin 100%
  • Cytoskeletal Crosstalk 100%
  • Microtubule 100%
  • Morphogenesis 75%

• The Role of LKB1 in the Specification of Neuronal Polarity

  Barnes, A. P. (Investigador principal)

  National Institute of Mental Health

  14/3/08 → 28/2/09

  Proyecto: Investigación

  • Neuronal Polarity 100%
  • Liver Kinase B1 (LKB1) 100%
  • Axon 50%
  • Cell Polarity 37%
  • Protein Serine Threonine Kinase 25%

• LPD Nanoparticles in Anti-Cancer Therapy

  Huang, L. (Investigador principal) & Huang, L. (CoPI)

  National Cancer Institute

  7/3/08 → 31/1/14

  Proyecto: Investigación

  • Anticancer Therapy 50%
  • Small Interfering RNA (siRNA) 50%
  • Malignant Neoplasm 50%
  • Nanoparticle 50%
  • Small Interfering RNA 50%

• Interaction of cationic lipids with dendritic cells

  Huang, L. (Investigador principal) & Huang, L. (CoPI)

  National Cancer Institute

  5/3/08 → 28/2/14

  Proyecto: Investigación

  • Cationic Lipids 100%
  • 1,2 Dioleoyl 3 Trimethylammoniopropane 100%
  • Dendritic Cells 50%
  • TC-1 Tumor 33%
  • Interleukin-12 (IL-12) 33%

• REU Site: Research Experiences for Undergraduates in Biodiversity Conservation

  Kelley, P. P. (Investigador principal) & Dietl, G. G. P. (CoPI)

  National Science Foundation

  1/3/08 → 28/2/13

  Proyecto: Investigación

  • Archaeological Record 100%
  • Fossil 100%
  • Undergraduate Research Experiences 74%
  • Marine Communities 74%
  • Biodiversity Conservation 74%

• SGER: Novel Ultra Fast Heating Platform for In-Situ Study of Nanoparticle Based Devices

  Misra, V. (Investigador principal)

  National Science Foundation

  1/3/08 → 28/2/09

  Proyecto: Investigación

  • In Situ Study 100%
  • Ultrafast Heating 100%
  • Coulomb Blockade 50%
  • Nanostructures 50%
  • Device Characteristics 50%

• Immunobiology of Acute Environmental Asthma

  Peden, D. B. (Investigador principal), Koller, B. H. (CoPI), Tilley, S. L. (CoPI) & Ting, J. P. Y. (CoPI)

  National Institute of Allergy and Infectious Diseases

  1/3/08 → 28/2/14

  Proyecto: Investigación

  • Asthma 100%
  • Inflammasome 75%
  • Caspase 1 75%
  • Interleukin 18 75%
  • CD14 50%

• Optimizing Immunogenicity of Lactobacillus as a Mucosal Vaccine Against HIV-1

  Dean, G. A. (Investigador principal)

  National Institute of Allergy and Infectious Diseases

  15/2/08 → 31/1/09

  Proyecto: Investigación

  • Immunogenicity 100%
  • Lactobacillus 100%
  • Mucosal Vaccine 100%
  • Human Immunodeficiency Virus 1 100%
  • Vaccine Efficacy 100%

• Correction of dF508 Cystic Fibrosis Using an Engineered Nuclease

  Jantz, D. (Investigador principal)

  National Heart, Lung, and Blood Institute

  15/2/08 → 14/8/09

  Proyecto: Investigación

  • Engineered nucleases 100%
  • ΔF508 100%
  • Allele 100%
  • Endonuclease 50%
  • Cystic Fibrosis 50%

• A Rhesus Macaque Model of SIV-Malaria Co-Infection

  De Paris, K. K. (Investigador principal) & Abel, K. (CoPI)

  15/2/08 → 31/1/09

  Proyecto: Investigación

  • Malaria Co-infection 100%
  • Rhesus Macaque Model 100%
  • Co-infection 100%
  • AIDS/HIV 100%
  • Simian Immunodeficiency Virus 100%

• Spatiotemporal Dynamics of RhoA Activation in Growth Cone Motility

  Vitriol, E. E. A. (CoPI) & Vitriol, E. A. (Investigador principal)

  National Institute of Neurological Disorders and Stroke

  15/2/08 → 14/2/09

  Proyecto: Investigación

  • RhoA Activation 100%
  • Growth Cone 100%
  • Spatiotemporal Dynamics 50%
  • Motility 50%
  • RhoA 28%

• BPC-AE: The STARS Alliance: A Southeastern Partnership for Broadening Participation in Computing

  Dahlberg, T. T. A. (Investigador principal) & Barnes, T. T. M. (CoPI)

  National Science Foundation

  1/2/08 → 31/1/13

  Proyecto: Investigación

  • Broadening Participation in Computing 100%
  • Regional Cooperation 100%
  • Academic Institution 100%
  • Geographic Region 100%
  • Junior Faculty 100%

• Grid-C: Green Research for Incorporating Data in the Classroom

  Deluca, W. W. V. (Investigador principal), Clark, A. A. (CoPI), Eckerlin, H. H. M. (CoPI), Carpenter, P. P. (CoPI) & Annetta, L. (CoPI)

  National Science Foundation

  1/2/08 → 31/1/10

  Proyecto: Investigación

  • Photovoltaic System 100%
  • Technology Education 33%
  • Wind Speed 33%
  • Renewable Energy Technologies 33%
  • Monitoring System 33%

• Collaborative Research: Supernova Simulation With CHIMERA

  Blondin, J. J. M. (Investigador principal)

  National Science Foundation

  1/2/08 → 30/6/11

  Proyecto: Investigación

  • Neutron Stars 100%
  • Linear Systems 100%
  • Gravitational Wave 100%
  • Physics 100%
  • Supernovae 100%

• Sex, Aging and Antiretroviral Pharmacology

  Patterson, K. B. (Investigador principal)

  National Institute of Allergy and Infectious Diseases

  1/2/08 → 31/1/13

  Proyecto: Investigación

  • Antiretroviral Pharmacology 100%
  • Aging 83%
  • HIV Patients 83%
  • Human Immunodeficiency Virus 83%
  • Genital Tract 83%