UNC Kenan-Flagler

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  Understanding the Contribution of Endothelial Lipid Droplet Metabolism in Cardiovascular Diseases

  Kim, B. B. (PI) & Kim, B. B. (CoPI)

  9/9/22 → 9/1/23

  Project: Research Project

  • Lipid Droplets 100%
  • Rate-limiting Enzyme 10%
  • Cell Culture 10%

• CAMELLIA Cohort: A longitudinal study to understand sexual health and prevention among women in Alabama

  Elopre, L. L. E. (PI) & Matthews, L. L. T. (CoPI)

  Eunice Kennedy Shriver National Institute of Child Health and Human Development

  8/9/22 → 31/8/24

  Project: Research Project

  • Deep South 66%

• Leveraging routinely collected health data to improve early identification of autism and co-occurring conditions

  Goldstein, B. A. (PI)

  Eunice Kennedy Shriver National Institute of Child Health and Human Development

  6/9/22 → 31/8/23

  Project: Research Project

  • Primary Health Care 23%
  • Clinical Decision Support Tool 20%
  • Clinical Setting 20%

• Studies of optical and chemical properties of aged and fresh biomass burning absorbing aerosols for climate models

  Bililign, S. S. (PI) & Fiddler, M. M. (CoPI)

  Biological and Environmental Research

  1/9/22 → 29/2/24

  Project: Research Project

  • Atmospherics 100%
  • Biomass Burning 100%
  • Light-absorbing Properties 33%
  • Particulate Matter Emissions 33%
  • Chemical Composition 16%

• Building research capacity in Southern Appalachian mountain wetlands

  Wilcox, J. J. (PI)

  Biological and Environmental Research

  1/9/22 → 30/4/24

  Project: Research Project

  • Mountain Wetlands 100%
  • Wetland Restoration 14%
  • Science System 7%

• Research Capacity Core

  Richardson, M. M. R. (PI)

  National Institute on Minority Health and Health Disparities

  1/9/22 → 31/8/23

  Project: Research Project

  • Health Disparities Research 55%
  • Research Infrastructure 55%
  • Behavioral Health 44%
  • Health Infrastructure 40%
  • Genome Analysis 11%

• Preventing Age-Associated Oocyte Aneuploidy: Mechanisms Behind the Drosophila melanogaster Centromere Effect

  Pazhayam, N. N. M. (PI)

  National Institute on Aging

  1/9/22 → 31/8/24

  Project: Research Project

  • Drosophila Melanogaster 66%
  • Co-suppression 6%
  • Chromosome Crossover 6%

• The Role of CSF Dynamics in Infant Brain and Behavioral Development in Down Syndrome and Related Neurodevelopmental Disorders

  Garic, D. D. (PI)

  Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institute of Child Health and Human Development

  1/9/22 → 31/8/24

  Project: Research Project

  • Early Brain Development 12%
  • Brain Health 8%

• Fibrin-CAR-T cells therapies to enhance efficacy in glioblastoma treatments

  Ogunnaike, E. E. (PI)

  National Institute of Neurological Disorders and Stroke

  1/9/22 → 31/8/24

  Project: Research Project

  • Chimeric Antigen Receptor T Cells (CAR-T) 66%
  • Glioblastoma multiforme 33%
  • Biocompatible Material 25%
  • Tumor Microenvironment 25%
  • Therapy Approaches 16%

• EASTERN BAND OF CHEROKEE INDIANS FEDERALLY RECOGNIZED TRIBES EXTENSION PROGRAM 2022

  Walker, R. R. R. R. (PI)

  National Institute of Food and Agriculture

  1/9/22 → 31/8/23

  Project: Research Project

  • Traditional Foods 100%
  • Support System 50%
  • Fruit Quality 25%
  • Production Techniques 20%
  • Community Partners 20%

• Intravesical Immunotherapy of Spontaneous Canine Invasive Urothelial Carcinoma

  Zaharoff, D. D. (PI) & Hess, P. P. R. (CoPI)

  National Cancer Institute

  1/9/22 → 31/8/24

  Project: Research Project

  • Invasive Urothelial Carcinoma 100%
  • Bladder Cancer 20%
  • Bladder Tumor 10%
  • Laboratory Test 10%
  • Tumor Immune Microenvironment 9%

• Approaches and Outcomes of Shared Decision-making and Patient Centered Care Delivery in Barrett's Esophagus

  Eluri, S. S. (PI)

  National Institute of Diabetes and Digestive and Kidney Diseases

  1/9/22 → 31/5/24

  Project: Research Project

  • National Institutes of Health 22%
  • Health Research 22%
  • Professional Occupations 22%
  • Content Validity 11%
  • Training Goals 11%

• Monitoring antimicrobial resistance (AMR) in enteric pathogens isolated from retail meats and seafoods in North Carolina

  Thakur, S. S. (PI)

  U.S. Food and Drug Administration

  1/9/22 → 31/8/24

  Project: Research Project

  • Retail Meat 66%
  • Escherichia coli 66%
  • Antimicrobial 53%
  • Vibrio 42%
  • Campylobacter Coli 20%

• FOOD ANIMAL RESIDUE AVOIDANCE DATABANK (FARAD)

  Jaberi-douraki, M. (PI)

  National Institute of Food and Agriculture

  1/9/22 → 31/8/23

  Project: Research Project

  • Animal Residues 100%
  • University of Kansas 50%
  • Information Retrieval 16%
  • Food Safety Program 16%
  • Comparative Medicine 16%

• Automated Data Collection on Antimicrobial Use in Dogs and Cats in a Tertiary Hospital and Private Practices

  Lanzas, C. (PI)

  U.S. Food and Drug Administration

  1/9/22 → 31/8/24

  Project: Research Project

  • Antimicrobial Use 66%
  • Dog 66%
  • Industry Partners 11%

• Prenatal stress and diet, and the fetal epigenome

  Hoyo, C. C. (PI)

  National Institute on Minority Health and Health Disparities

  1/9/22 → 31/3/24

  Project: Research Project

  • Parent-of-origin 20%
  • Metabolism 13%
  • Environmental Exposure 13%

• Nutritional Regulation of Luteinizing Hormone Secretion

  Nestor, C. C. C. (PI)

  Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institute of Child Health and Human Development

  1/9/22 → 31/7/24

  Project: Research Project

  • Microglia 6%
  • Reproductive Success 6%
  • Cell Culture 6%
  • Immunohistochemistry 6%

• CC* Data Storage: Flexible Affordable Scalable Technology for Research Storage (FAST-Research Storage)

  Futhey, T. (CoPI), Boyer, D. (CoPI), Futhey, T. (CoPI), Bartesaghi, A. (PI) & Bartesaghi, A. (CoPI)

  National Science Foundation

  1/9/22 → 31/8/24

  Project: Research Project

  • Consumption Stage 50%
  • Object Storage 25%

• The Human Lung BioMolecular Multi-Scale Atlas Program (HuBMAP-Lung)

  Pryhuber, G. G. S. (PI)

  National Heart, Lung, and Blood Institute

  1/9/22 → 31/8/24

  Project: Research Project

  • Gene Expression 100%
  • Transcriptomics 80%
  • Tabular Data 14%
  • Network Connection 11%
  • High Sensitivity 11%

• Peer Support for Lowering Blood Pressure among Adolescents: A Pilot, Randomized Controlled Trial

  Hardy, S. S. T. (PI)

  National Heart, Lung, and Blood Institute

  1/9/22 → 31/8/24

  Project: Research Project

  • Adolescent 50%
  • Experiential Learning 25%
  • Academic Scientists 20%
  • Co-payment 20%
  • Clinical Setting 13%

• The Role of Kaiso as a predictive breast cancer biomarker in Africa and across the African Diaspora

  Gardner, K. K. L. (PI)

  National Cancer Institute

  1/9/22 → 31/8/24

  Project: Research Project

  • Gene Expression 33%
  • Anticancer Immune Response 25%
  • Predictive Value 12%
  • Survival Response 12%
  • Tumor Microenvironment 9%

• Adapting a point of use test card, the chemoPAD, for protecting chemotherapy drug quality in sub-Saharan Africa

  Lieberman, M. M. (PI)

  National Cancer Institute

  23/8/22 → 31/7/24

  Project: Research Project

  • Mobile Phone Application 60%
  • Malawi 40%
  • Technical Capacity 20%

• Investigating SARS-CoV-2 transmission dynamics in jails to address the COVID-19 public health emergency

  Levintow, S. S. N. (PI)

  National Institute of Allergy and Infectious Diseases

  22/8/22 → 31/7/24

  Project: Research Project

  • SARS-CoV-2 Transmission 100%
  • Vulnerable Population 11%

• Computational tools and quantitative analyses of genome structure evolution

  Guerrero, R. R. F. (PI)

  National Institute of General Medical Sciences

  18/8/22 → 30/6/24

  Project: Research Project

  • Genomic Structure 66%
  • Sex Chromosome System 22%
  • Evolution of Sex 16%
  • Anopheles Gambiae 12%
  • Population Genomics 12%

• Novel Deep Learning Tools for Clinical Decision Support in Postoperative Pain Management

  Zou, B. (PI)

  U.S. National Library of Medicine

  16/8/22 → 31/7/24

  Project: Research Project

  • Management Interventions 50%
  • Interweaving 50%
  • Intensity Score 50%

• Tobacco-based Sustainable Squalene for Novel Vaccine Adjuvant Emulsions

  Gorman, C. C. R. (PI)

  National Institute of Allergy and Infectious Diseases

  15/8/22 → 31/7/23

  Project: Research Project

  • Microbiology 25%
  • T Cell Activation 12%
  • Leaf Surface 12%
  • U.S. Food 8%
  • Health Care Cost 6%

• Zeiss LSM 980 Confocal Microscope

  Itano, M. M. S. (PI)

  NIH Office of the Director

  15/8/22 → 14/8/23

  Project: Research Project

  • Microscopy 75%
  • Ariel 50%
  • Cellular Compartment 33%
  • Optical Sectioning 25%
  • School of Medicine 25%

• Catalyst Project: Age and temperature-dependent millimeter-wave charge carrier dynamics in hybrid perovskite films

  Roy, B. (PI)

  National Science Foundation

  15/8/22 → 31/7/24

  Project: Research Project

  • Experimental Data Collection 50%
  • Millimeter-wave Frequency 50%
  • Non-radial 50%
  • Photodetection 50%
  • Positive Peak 33%

• Systems biology of quiescence entry

  Argüello-miranda, O. O. (PI)

  National Institute of General Medical Sciences

  3/8/22 → 31/7/24

  Project: Research Project

  • Cell Cycle Regulation 33%
  • DNA Replication 33%
  • Platform-Based 14%
  • Imaging Systems 9%
  • Machine Time 9%

• Activity-Enhanced Self-Assembly of Colloidal-Based Materials

  Klotsa, D. D. (PI)

  Basic Energy Sciences

  1/8/22 → 31/1/25

  Project: Research Project

  • Material Development 50%
  • Synthetic System 50%
  • Self Assembly 50%

• Super Resolution STED Microscopy at UNC

  Gupton, S. S. (PI)

  NIH Office of the Director

  1/8/22 → 31/7/23

  Project: Research Project

  • High Resolution 25%
  • School of Medicine 16%
  • Professional School 16%

• High Resolution Fluorescence Imaging of Dense Brain Regions with Dual Selective Plane Illumination Microscopy

  Itano, M. M. S. (PI)

  National Institute of Mental Health

  1/8/22 → 31/7/23

  Project: Research Project

  • Molecular Imaging 50%
  • Selective Plane Illumination 33%
  • Embryonic Brain 16%
  • Ariel 16%
  • School of Medicine 16%

• Drug Retention and Tumor Distribution of Polymeric Micelles for Cancer Therapy

  Ramsey, J. J. D. (PI)

  National Cancer Institute

  1/8/22 → 31/7/24

  Project: Research Project

  • Fraction Unbound 12%
  • Human-like 12%
  • Nonhuman Primate 8%
  • Mouse Model 6%

• Collaborative Research: Mathematical and Experimental Analysis of Competitive and Predator-Prey Models: Conditional Dispersal on Patches to Landscapes

  Shivaji, R. R. (PI)

  National Science Foundation

  1/8/22 → 31/7/23

  Project: Research Project

  • Competing Species 50%
  • Population Dynamics 37%
  • Lotka-Volterra Competition 25%
  • Ecologists 12%
  • Mathematical Modeling 12%

• Upgrade of Bruker Time-domain EPR Spectrometer

  Smirnov, A. A. I. (PI)

  NIH Office of the Director

  1/8/22 → 31/7/23

  Project: Research Project

  • Time Domain 50%
  • Protein Complex 25%
  • Atomic Level 25%

• PIPP Phase I: Real-time Analytics to Monitor and Predict Emerging Plant Disease

  Ristaino, J. B. (CoPI), Carbone, I. (CoPI), Delborne, J. A. (CoPI), Delborne, J. A. (CoPI) & Ristaino, J. B. (PI)

  National Science Foundation

  1/8/22 → 31/1/25

  Project: Research Project

  • Emerging Plant Disease 50%
  • Pandemic Preparedness 22%
  • Remote Sensing 9%
  • Social Sciences 5%
  • Poverty 5%

• The Don S. Fredrickson Lipid Research Conference

  Graf, G. A. (PI)

  National Heart, Lung, and Blood Institute

  1/8/22 → 31/7/23

  Project: Research Project

  • Clinical Significance 25%
  • Metabolism Disease 14%
  • Host Model 7%
  • Dyslipidemia 7%
  • Adipose Tissue 7%

• Light-Activated Silver Nanoparticles to Eliminate Antibiotic Resistant Bacteria and Genes

  Vivero-escoto, J. J. L. (PI)

  National Institute of General Medical Sciences

  1/8/22 → 31/7/24

  Project: Research Project

  • Tunable Surface Properties 11%
  • Effective Treatment 7%
  • Antimicrobial 7%

• Stimuli-responsive mucin1-specific nanoparticles for efficacious combinatorial chemotherapy of pancreatic ductal adenocarcinoma

  Vivero-escoto, J. J. L. (PI)

  National Cancer Institute

  1/8/22 → 31/7/24

  Project: Research Project

  • Gemcitabine Plus Cisplatin 100%
  • Pancreas Adenocarcinoma 100%
  • Effective Treatment 40%
  • Resistant Behavior 20%
  • 5-year Survival 20%

• SPLENDOR-NC Supplement to Develop the BRIDGES Consortium Brand Guide and Website

  Mayer-davis, E. J. (PI), Ongeri, E. E. M. (CoPI) & Shaikh, S. S. R. (CoPI)

  National Institute of Diabetes and Digestive and Kidney Diseases

  15/7/22 → 31/5/24

  Project: Research Project

  • Scientific Contribution 14%
  • School of Medicine 14%
  • Proposal Submission 14%

• Enhanced intratympanic delivery of therapeutics to treat and prevent hearing loss using nanovesicles in the porcine model

  Moatti, A. A. (PI)

  National Institute on Deafness and Other Communication Disorders

  15/7/22 → 30/6/24

  Project: Research Project

  • Pig 100%
  • Exosomes 18%
  • Drug Screening 6%

• LUMICKS C-TRAP

  Schmidt, C. C. F. (PI)

  NIH Office of the Director

  15/7/22 → 14/7/23

  Project: Research Project

  • Filopodia 100%
  • School of Medicine 25%

• Single cell, genome wide dissection of dynamic transcription factor regulation

  Caywood, L. L. (PI)

  National Cancer Institute

  11/7/22 → 10/7/24

  Project: Research Project

  • Polymerase 25%
  • Immunological Response 25%
  • Biomedical Applications 25%
  • Mammalian Synthetic Biology 25%
  • Transcriptome 14%

• Characterizing Gene-Environment Interactions that Affect Individual Susceptibility to an Expanding Chemical Exposome

  Wright, F. F. A. (PI) & Reif, D. M. (CoPI)

  National Institute of Environmental Health Sciences

  8/7/22 → 30/4/24

  Project: Research Project

  • Vulnerable Population 33%
  • Phenotypic Variation 25%

• Establishing Foundations to Develop a Treatment Decision Aid for Patients Hospitalized with Unexpected End-Stage Kidney Disease: A Community Engaged Approach

  Urbanski, M. M. (PI)

  National Institute of Diabetes and Digestive and Kidney Diseases

  1/7/22 → 30/6/23

  Project: Research Project

  • Central Venous Catheter 7%

• UNC-CH Training Program in Health Services Research

  Holmes, G. G. M. (PI)

  Agency for Healthcare Research and Quality

  1/7/22 → 30/6/24

  Project: Research Project

  • Outcomes Research 14%
  • Program Director 14%
  • Contract Research Organization 8%
  • Program Directors 8%
  • National Institutes of Health 8%

• Novel Sequencing Based Diagnostics for Leukemia in Low Resource Settings

  Alexander, T. T. B. (PI) & Wang, J. J. R. (CoPI)

  National Cancer Institute

  1/7/22 → 30/6/24

  Project: Research Project

  • Health Care Cost 33%
  • Malawi 26%
  • Capital Investment 20%
  • Multidisciplinary Groups 20%
  • Computational pipeline 20%

• High Throughput Clonal Analyses of Gliogenesis in Neocortical and Paleocortical areas of the Mouse Brain

  Ghashghaei, H. T. (PI) & Greenbaum, A. A. (CoPI)

  National Institute of Neurological Disorders and Stroke

  1/7/22 → 30/6/24

  Project: Research Project

  • Gliogenesis 100%
  • Cerebral Cortex 16%
  • Tracing Technique 8%
  • Brain Tumor 8%

• Enhance the surveillance of foodborne bacterial pathogens isolated from food and environmental samples using whole genome sequencing (WGS) to prevent foodborne outbreaks and promote public health

  Thakur, S. S. (PI)

  U.S. Food and Drug Administration

  1/7/22 → 30/6/24

  Project: Research Project

  • Environmental Samples 66%
  • Genome Analysis 13%
  • Retail Meat 13%

• Matching and Data Integration

  Ma, Z. (PI)

  National Science Foundation

  1/7/22 → 31/10/23

  Project: Research Project

  • Implementation Method 50%
  • Modeling Method 50%
  • Scientific Community 50%
  • Privacy Awareness 50%