UNC Kenan-Flagler

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  Rodent Metabolic Phenotyping System

  Neufer, P. P. D. (PI)

  NIH Office of the Director

  1/6/23 → 31/5/24

  Project: Research Project

  • Metabolic Cage 75%
  • Rodents 50%
  • PromethION 50%
  • Bioenergy 50%
  • Phenotype 50%

• Research Capacity Core

  Richardson, M. M. R. (PI)

  National Institute on Minority Health and Health Disparities

  1/6/23 → 31/5/24

  Project: Research Project

  • Research Capacity 100%
  • Research Project 40%
  • Health Services Research 40%
  • Population Health 22%
  • Medical Sciences 20%

• I-Corps: Medication Adherence System

  Dorodchi, M. M. (PI)

  National Science Foundation

  1/6/23 → 30/11/24

  Project: Research Project

  • I-Corps 74%
  • Documentation Purpose 74%
  • Drug Therapy 74%
  • Healthcare Professionals 50%
  • Patient Identification 50%

• Development of Ultrafast Timing Detectors Using Wide Band Gap Semiconductor Materials

  Muth, J. J. F. (PI), Pavlidis, S. S. (CoPI), Haber, C. (CoPI) & Holland, S. S. (CoPI)

  High Energy Physics

  1/6/23 → 31/3/25

  Project: Research Project

  • Ultrafast Timing 100%
  • Timing Detectors 100%
  • Cooling System 100%
  • Energy Gap 100%
  • Semiconductor (Material) 100%

• Evaluating dendritic DJ-1 targets as a framework for identifying pharmacotherapies for TSC-related neurological disorders

  Niere, F. F. (PI)

  National Institute of Neurological Disorders and Stroke

  20/5/23 → 30/4/24

  Project: Research Project

  • Rapamycin 100%
  • Neurologic Disease 100%
  • Disease 35%
  • Autism Disorder 28%
  • Scientific Workforce 14%

• I-Corps: An Artificial Intelligence-Driven Wearable Sensor-Based System for Precision Rehabilitation

  Saul, K. R. (PI)

  National Science Foundation

  15/5/23 → 31/10/24

  Project: Research Project

  • Rehabilitation Engineering 100%
  • Artificial Intelligence 100%
  • Osteoarthritis 100%
  • Wearable Sensor 100%
  • Wearable Sensors 50%

• Wearable, Wireless Deep-tissue Sensing Patch for Continuous Monitoring of Recovery from Microsurgical Tissue Transfer

  Bai, W. W. (PI)

  National Institute of Biomedical Imaging and Bioengineering

  1/5/23 → 30/4/24

  Project: Research Project

  • Tissue Transfer 100%
  • Flaps 100%
  • Wireless 50%
  • Continuous Monitoring 50%
  • Microsurgery 50%

• CAREER: Mathematical Modeling to Identify New Regulatory Mechanisms of Blood Clotting

  Leiderman, K. (PI)

  National Science Foundation

  1/5/23 → 30/6/24

  Project: Research Project

  • Blood Clot 100%
  • Mathematical Modeling 100%
  • Biochemicals 60%
  • Clot 57%
  • Mathematical Model 42%

• Perinatal Per- and Polyfluoroalkyl Substances (PFAS) exposure and Immunotoxicity in early life

  Feng, L. L. (PI)

  National Institute of Environmental Health Sciences

  20/4/23 → 31/1/24

  Project: Research Project

  • Immunotoxicity 100%
  • Polyfluoroalkyl Substances 50%
  • Progeny 50%
  • Immune Response 33%
  • Perfluorobutane 33%

• I-Corps: Instant Sediment Grain Size Measurements

  Goldstein, E. B. (PI)

  National Science Foundation

  15/4/23 → 31/3/24

  Project: Research Project

  • Sediment Grain Size 100%
  • Grain Size 100%
  • Coastal Engineering 66%
  • I-Corps 50%
  • Field Measurement 33%

• Development of an INSPIRE System for the Treatment of Inoperable Liver Tumors

  Sano, M. M. B. (PI)

  National Cancer Institute

  14/4/23 → 31/3/24

  Project: Research Project

  • Liver Tumor 100%
  • Thermal Injury 66%
  • Pulse Generator 25%
  • Inoperable Tumor 25%
  • Temperature Feedback 25%

• Deciphering the processes of adaptation and exaptation driving the evolution of opportunism in bacteria

  Raymann, K. (PI)

  National Institute of General Medical Sciences

  13/4/23 → 31/3/24

  Project: Research Project

  • Bacterial Evolution 100%
  • Opportunism 100%
  • Exaptation 100%
  • Apis mellifera 100%
  • Selective Pressure 50%

• Evidence-based Nutrition Education and Research Guidance (ENER-G)

  Zwickey, H. H. L. (PI), Johnston, B. B. (CoPI) & Allred, C. C. D. (CoPI)

  National Institute of Diabetes and Digestive and Kidney Diseases

  1/4/23 → 30/3/24

  Project: Research Project

  • Evidence-based nutrition 100%
  • Nutrition Education 100%
  • Nutrition Research 50%
  • Meta-Analysis 40%
  • Nutritionist 33%

• Preclinical Vevo-F2 ultrasound imaging system for Small Animal Imaging core facility

  Yuan, H. H. (PI)

  NIH Office of the Director

  1/4/23 → 31/3/24

  Project: Research Project

  • Small Animal Imaging 100%
  • Imaging Equipment 66%
  • SPECT-CT 33%
  • University of North Carolina 33%
  • Oncology 33%

• Anti-microbial platelet-like-particles to treat internal bleeding and augment subsequent healing

  Brown, A. A. C. (PI)

  National Heart, Lung, and Blood Institute

  1/4/23 → 31/3/24

  Project: Research Project

  • Internal Bleeding 100%
  • Platelet Particles 50%
  • Antiinfective Agent 50%
  • Bleeding 50%
  • Clot Contraction 42%

• Developing Therapeutic Gel Embolic Agents for Arteriovenous Malformation Embolization

  Hu, J. J. (PI)

  National Institute of Biomedical Imaging and Bioengineering

  1/4/23 → 31/3/24

  Project: Research Project

  • Arteriovenous Malformation Embolization 100%
  • Embolization 50%
  • AVM Rupture 16%
  • N-butyl Cyanoacrylate 16%
  • Biosafety Assessment 16%

• Deciphering molecular mechanisms controlling age-associated uterine adaptabilityto pregnancy

  Wang, X. X. (PI)

  Eunice Kennedy Shriver National Institute of Child Health and Human Development

  1/4/23 → 31/1/24

  Project: Research Project

  • Decidualization 100%
  • Cofactor 66%
  • Progesterone 66%
  • Reproductive Aging 50%
  • Genetics 33%

• Enteric Glia is New Biological Target to Block Drug Resistance in Colon Cancer

  Van Landeghem, L. L. C. (PI)

  National Cancer Institute

  1/4/23 → 31/3/24

  Project: Research Project

  • Biological Targets 100%
  • FSTL3 100%
  • Biological Target 100%
  • Glia 100%
  • Drug Resistance 50%

• Predicting firearm suicide in military veterans outside the VA health system using linked civilian electronic health record data

  Swanson, J. J. W. (PI) & Kimbrel, N. N. A. (CoPI)

  National Institute of Mental Health

  1/4/23 → 31/3/24

  Project: Research Project

  • Death Record 50%
  • Social Indicator 50%
  • Civilian Population 50%
  • VA Health Care System 50%
  • Suicide 50%

• Role of extracellular vesicles in assaying and regulating immune dysfunction after burn injury

  Willis, M. M. L. (PI)

  National Institute of General Medical Sciences

  15/3/23 → 14/3/24

  Project: Research Project

  • Immune Disorder 100%
  • Extracellular Vesicles 50%
  • Cytokine 28%
  • Damage-associated Molecular Patterns 25%
  • Mediator 20%

• Collaborative Research: Conference: Supporting inclusive and sustainable research infrastructure for systematics (SISRIS) by connecting scientists and their specimens.

  Zeringue-krosnick, S. E. (PI) & Majors, T. D. (CoPI)

  National Science Foundation

  15/3/23 → 29/2/24

  Project: Research Project

  • Sustainable Research 100%
  • Collaborative Research 100%
  • Taxonomic Knowledge 100%
  • Inclusive Research 100%
  • Research Meeting 100%

• Circuit mechanisms for opioid analgesia and addiction in prefrontal cortex

  Ochandarena, N. N. E. (PI)

  National Institute on Drug Abuse

  1/3/23 → 29/2/24

  Project: Research Project

  • Prefrontal Cortex 100%
  • Pyramidal Tract 100%
  • Circuit Mechanisms 100%
  • Opiate 100%
  • Medial Prefrontal Cortex (mPFC) 70%

• Development of a conditional ataxin-1 knockout mouse line

  Didonna, A. A. (PI)

  National Institute of Neurological Disorders and Stroke

  15/2/23 → 31/1/24

  Project: Research Project

  • Ataxin 1 100%
  • Knock-in Mouse Model 50%
  • Multiple Sclerosis 14%
  • CRISPR 7%
  • CD19 7%

• Engineering locus-specific binders to DNA modifications

  Keung, A. (PI)

  National Institute of General Medical Sciences

  1/2/23 → 31/1/24

  Project: Research Project

  • Binder 50%
  • DNA Hydroxymethylation 25%
  • Epigenetic Modification 25%
  • Kingdoms of Life 25%
  • Nucleic Acids 12%

• Dyadic Analysis of Unmet Social Needs Among Breast and Gynecologic Patients and Their Informal Caregivers

  Thompson, T. T. (PI)

  19/1/23 → 31/12/23

  Project: Research Project

  • Breast 100%
  • Dyadic Analysis 100%
  • Caregiver 100%
  • Cancer Patients 33%
  • Quality of Life 25%

• Collaborative Research: Analysis and Control in Multi-Scale Interface Coupling between Deformable Porous Media and Lumped Hydraulic Circuits

  Guidoboni, G. G. (PI)

  National Science Foundation

  15/1/23 → 31/7/24

  Project: Research Project

  • Collaborative Research 100%
  • Research Analysis 100%
  • Glaucoma 100%
  • Blood Pressure 100%
  • Intraocular Pressure 66%

• A Novel Large Animal Model for Studying the Developmental Potential and Function of LGR5 Stem Cells in Vivo and in Vitro

  Piedrahita, J. J. A. (PI)

  NIH Office of the Director

  1/1/23 → 30/11/23

  Project: Research Project

  • Lgr5 100%
  • Lgr5+ Stem Cells 100%
  • Stem Cell 100%
  • Adult Stem Cell 50%
  • Lineages 50%

• Collaborative Research: CyberTraining: Pilot: A Cybertraining Program to Advance Data Acquisition, Processing, and Machine Learning-based Modeling in Marine Science

  Liu, Q. (PI), Dogan, G. (CoPI), Song, Y. (CoPI) & Wang, Z. (CoPI)

  National Science Foundation

  1/1/23 → 31/12/24

  Project: Research Project

  • Collaborative Research 50%
  • Data-driven Workflow 42%
  • Building Process 14%
  • Data Engineering 14%
  • Computational Power 14%

• Fueling left-right asymmetry: the role of glycolysis in stomach curvature

  Nascone-yoder, N. N. M. (PI)

  Eunice Kennedy Shriver National Institute of Child Health and Human Development

  1/1/23 → 31/12/23

  Project: Research Project

  • Left-right Asymmetry 100%
  • Morphogenesis 100%
  • Laterality 50%
  • Mitochondrial Respiration 25%
  • Gene Function 25%

• International Neurotoxicology Association (INA) Conference

  Levin, E. E. D. (PI)

  National Institute of Environmental Health Sciences

  17/12/22 → 16/12/23

  Project: Research Project

  • Neurotoxicology 100%
  • Neurotoxicity 40%
  • High-throughput 6%
  • New Approach Methodologies 6%
  • Israel 6%

• Mechanism of APE2 in genome integrity

  Yan, S. S. (PI)

  National Cancer Institute

  15/12/22 → 30/11/23

  Project: Research Project

  • Apyrimidinic Site 60%
  • Xenopus 60%
  • Genome Integrity 50%
  • Genome Instability 40%
  • Carcinogenesis 20%

• Convergence Accelerator Track J: Convergence Towards a Disaster Resilient Food System

  Milburn, A. B. (CoPI), Clay, L. (PI), Prentice, C. (CoPI) & Waity, J. F. (CoPI)

  National Science Foundation

  15/12/22 → 30/11/24

  Project: Research Project

  • Convergence Accelerators 100%
  • Food Security 78%
  • Resilience 50%
  • Food Index 50%
  • Community-based 28%

• MRI: Acquisition of a High-Speed Biplanar Fluoroscopy System for Non-Invasive Quantitative Imaging of Human Movement

  Blackburn, J. T. J. T. (PI), Saul, K. (CoPI), Huang, H. H. (CoPI), Pietrosimone, B. (CoPI) & Saul, K. R. (CoPI)

  National Science Foundation

  1/11/22 → 31/10/24

  Project: Research Project

  • Biplane Fluoroscopy 100%
  • Quantitative Imaging 100%
  • MRI Acquisition 50%
  • Magnetic Resonance Imaging 50%
  • Chapel Hill 25%

• Collaborative Research: PPoSS: Planning: Cross-layer Coordination and Optimization for Scalable and Sparse Tensor Networks (CROSS)

  Li, J. (PI)

  National Science Foundation

  1/10/22 → 30/9/24

  Project: Research Project

  • Collaborative Research 100%
  • Tensor Network 100%
  • High-dimensional Data 37%
  • High Dimensional Data 30%
  • Tensor Networks 25%

• SaTC: CORE: Small: Partition-Oblivious Real-Time Hierarchical Scheduling

  Kim, J.-E. (CoPI) & Yoon, M.-K. (PI)

  National Science Foundation

  1/10/22 → 31/3/24

  Project: Research Project

  • Temporal Behavior 40%
  • Non-interference 40%
  • Algorithmic Solution 20%
  • Faulty Operation 20%
  • Hardware Technology 20%

• EAGER: A novel route for high activation of implanted p-type regions in vertical Gallium Nitride devices.

  Misra, V. (PI) & Lee, B. (CoPI)

  National Science Foundation

  1/10/22 → 31/3/24

  Project: Research Project

  • Gallium Nitride Device 100%
  • Gallium Nitride 100%
  • Solid Phase Epitaxy 70%
  • Power Device 60%
  • P-type Dopant 37%

• Collaborative Research: PPoSS: Planning: Cross-layer Coordination and Optimization for Scalable and Sparse Tensor Networks (CROSS)

  Mueller, F. F. (PI)

  National Science Foundation

  1/10/22 → 30/9/24

  Project: Research Project

  • Tensor Network 100%
  • Collaborative Research 50%
  • High-dimensional Data 37%
  • High Dimensional Data 30%
  • Tensor Networks 25%

• Re-engineering Postnatal Unit Care and the Transition Home to Reduce Perinatal Morbidity and Mortality

  Stuebe, A. A. M. (PI) & Tully, K. K. P. (CoPI)

  Agency for Healthcare Research and Quality

  30/9/22 → 29/9/23

  Project: Research Project

  • Perinatal Mortality 100%
  • Perinatal Morbidity 100%
  • Postnatal Care 100%
  • Antenatal Care 50%
  • United States 33%

• Unpacking Disparities in Opioid Use Disorder Treatment Quality

  Domino, M. M. E. (PI)

  National Institute on Drug Abuse

  30/9/22 → 31/7/24

  Project: Research Project

  • Combination Therapy 66%
  • Quality of Care 19%
  • Drug Therapy 9%
  • Capitation 7%
  • Gender Groups 7%

• RFA-CK-22-008, Building Next-generation Mathematical Biology Modeling Workforce for HAI Control

  Chen, S. S. (PI)

  National Center for Emerging and Zoonotic Infectious Diseases

  30/9/22 → 29/9/24

  Project: Research Project

  • Mathematical Biology 100%
  • Research Project 66%
  • Health Economics 50%
  • Connectedness 50%
  • Transdisciplinary 50%

• NCCU RCMI Practice Based Equity Research Network (PBERN)

  Kumar, D. D. (PI)

  National Institute on Minority Health and Health Disparities

  25/9/22 → 30/6/24

  Project: Research Project

  • Equity Research 100%
  • Clinical Research 100%
  • Implementation Research 53%
  • Health Center 50%
  • Health Service 33%

• Academic-Industrial Partnership to Develop Clinical Tools for Algorithmic Irreversible Electroporation of Inoperable Tumors

  Sano, M. M. B. (PI)

  National Cancer Institute

  22/9/22 → 31/8/24

  Project: Research Project

  • Inoperable Tumor 100%
  • Clinical Tool 100%
  • Medical Devices 66%
  • Pulsed Electric Field 33%
  • Veterinarians 33%

• A Career Development Award in Global Postpartum Health

  Spelke, M. B. M. (PI)

  Fogarty International Center

  21/9/22 → 30/4/24

  Project: Research Project

  • Maternal Morbidity 100%
  • Premature Labor 50%
  • Physiologic Monitoring 50%
  • Gynecologist 50%
  • International Research 33%

• Substance P exacerbation of staphylococcal bone damage

  Marriott, I. (PI) & Johnson, M. B. (CoPI)

  National Institute of Allergy and Infectious Diseases

  19/9/22 → 31/7/24

  Project: Research Project

  • Bone Damage 100%
  • Substance P 100%
  • Osteomyelitis 80%
  • Bone Cells 60%
  • Bone Loss 40%

• Establishing the pig as a large animal model for studying drug delivery to the inner ear

  Greenbaum, A. A. (PI)

  National Institute on Deafness and Other Communication Disorders

  16/9/22 → 31/7/24

  Project: Research Project

  • Inner Ear 66%
  • Hearing Impairment 66%
  • Pig 40%
  • Drug Penetration 20%
  • Social Isolation 20%

• Discovery of genetic modifiers of PTEN-ASD severity in a library of genetically diverse iPSC lines

  Wolter, J. J. (CoPI)

  16/9/22 → 31/8/24

  Project: Research Project

  • Genetics 100%
  • Autism Spectrum Disorder 100%
  • Magnetic Resonance Imaging 50%
  • PTEN mutation 40%
  • Penetrant 40%

• Development of LED Photoredox Radiolabeling Device

  Wu, X. X. (PI)

  National Institute of Biomedical Imaging and Bioengineering

  15/9/22 → 14/9/23

  Project: Research Project

  • Photoredox 100%
  • Polycyclic Aromatic Hydrocarbon 50%
  • Positron 50%
  • Drug 25%
  • Drug Discovery 25%

• Excellence in Research: Privacy preserved data fusion for personalized recommendation in an Edge-assisted IoT smart health network

  Siddula, M. (PI)

  National Science Foundation

  15/9/22 → 31/8/24

  Project: Research Project

  • User Behavior 100%
  • Smart Health 100%
  • Edge-assisted IoT 100%
  • Health Sensors 100%
  • Preserved Data 100%

• Improving Primary Care Clinicians’ Advance Care Planning for Persons Living with Alzheimer’s Disease and Related Dementias

  Kistler, C. C. E. (CoPI) & Kistler, C. C. E. (PI)

  15/9/22 → 31/8/24

  Project: Research Project

  • Advance Care Planning 100%
  • Alzheimer's Dementia 100%
  • Clinician 100%
  • Disease-related 71%
  • Dementia 14%

• Project 1: The Reciprocal Relationship between Binge Drinking and Astrocytic Signaling

  Marshall, S. S. A. (PI)

  National Institute on Alcohol Abuse and Alcoholism

  10/9/22 → 31/8/23

  Project: Research Project

  • Neuroimmune Response 50%
  • Proinflammatory Cytokine 40%
  • Hippocampus 30%
  • DREADD 25%
  • Excessive Consumption 25%