UNC Kenan-Flagler

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  RI: Small: Foundations of Ethics for Multiagent Systems

  Singh, M. M. P. (PI)

  National Science Foundation

  1/10/21 → 30/9/24

  Project: Research Project

  • Multi-agent 30%
  • Thinking in Threes 20%
  • Individual Agent 20%
  • Mutual Interaction 10%
  • Ethical Issues 10%

• Collaborative Research: CNS Core: Small: Timely Computing and Learning over Communication Networks

  Arafa, A. A. (PI)

  National Science Foundation

  1/10/21 → 30/9/24

  Project: Research Project

  • Low Latency 40%
  • Federated Learning System 20%
  • Latency Efficient 20%
  • Learning-based 20%
  • Information Sharing System 20%

• Fructose Induced Regulation of Profibrogenic Factors in Hepatic Nonparenchymal Cells

  Kennedy, A. A. (PI)

  National Institute of Diabetes and Digestive and Kidney Diseases

  24/9/21 → 31/8/24

  Project: Research Project

  • Pro-fibrogenic 100%
  • Fructose 100%
  • Cell Function 22%
  • Disease 16%
  • Oxidative Stress 15%

• Fully defined matrices for organoid culture

  Roberts, S. (PI)

  National Institute of Diabetes and Digestive and Kidney Diseases

  21/9/21 → 31/8/22

  Project: Research Project

  • Organoid Culture 100%
  • Matrigel 42%
  • Ex Vivo Tissues 20%
  • 3D Culture System 20%
  • Life Sciences 20%

• Southern Liver Health Cohort

  Hoyo, C. C. (PI), Moylan, C. C. A. (CoPI) & Schildkraut, J. M. (CoPI)

  National Cancer Institute

  21/9/21 → 31/8/23

  Project: Research Project

  • Liver Cell Carcinoma 100%
  • Liver Health 66%
  • Hepatocellular Carcinoma 33%
  • Liver Cirrhosis 24%
  • Fibrosis 24%

• Prediction and Prevention of Hepatic Decompensation in Patients with Cirrhosis

  Diehl, A. M. A. E. (PI), Abdelmalek, M. (CoPI) & Moylan, C. C. A. (CoPI)

  National Institute of Diabetes and Digestive and Kidney Diseases

  20/9/21 → 31/7/24

  Project: Research Project

  • Decompensated Liver Cirrhosis 100%
  • Hepatic Decompensation 80%
  • Liver Dysfunction 19%
  • Nonalcoholic Fatty Liver 8%
  • Metabolic Syndrome 8%

• Neonatal gut-on-a-chip platform for high content drug testing and precision medicine

  Good, M. M. L. (PI), Magness, S. T. (CoPI), Good, M. L. (CoPI) & Luke, C. J. (CoPI)

  20/9/21 → 31/8/24

  Project: Research Project

  • Drug Testing 100%
  • Precision Medicine 100%
  • Drug Screening 100%
  • Organoid 100%
  • Prematurity 100%

• SCH: A personalized wearable rehabilitation sensing system for stroke survivors

  Zhu, Y. Y. (PI), Bozkurt, A. A. (CoPI), Baratta, J. J. (CoPI), Hu, X. X. (CoPI) & Shen, X. X. (CoPI)

  Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institute of Child Health and Human Development

  17/9/21 → 31/8/24

  Project: Research Project

  • Sensing System 75%
  • Rehabilitation Engineering 75%
  • Apoplexy 75%
  • Daily Functioning 28%
  • Community-based Rehabilitation 25%

• ATM activation by DNA single-strand breaks

  Yan, S. S. (PI)

  National Institute of Environmental Health Sciences

  17/9/21 → 31/8/23

  Project: Research Project

  • ATM Activation 100%
  • Single-strand Breaks 66%
  • Egg Extract 66%
  • Single Stranded DNA 66%
  • Genome Instability 50%

• D1 dopamine receptor positive allosteric modulators as a practical treatment for cognitive decline

  Frankowski, K. J. (PI)

  National Institute on Aging

  15/9/21 → 31/5/23

  Project: Research Project

  • Cognitive Decline 50%
  • D1 Dopamine Receptor 50%
  • Allosteric Site 25%
  • Cognitive Function 12%
  • Prefrontal Cortex 8%

• Long-term alcohol drinking alters stress engagement of BNST circuit elements

  Hwa, L. S. (PI)

  National Institute on Alcohol Abuse and Alcoholism

  15/9/21 → 31/8/23

  Project: Research Project

  • Alcohol Drinking 100%
  • Stria Terminalis 100%
  • Predator Odor 36%
  • Neuroscience 36%
  • Κ-opioid receptor 18%

• REU SITE: Collaborative Research: Nanoscale Detectives -- Elucidating the Structure and Dynamics of Hybrid Perovskite Systems

  Amassian, A. A. (PI)

  National Science Foundation

  15/9/21 → 31/8/24

  Project: Research Project

  • Perovskite Systems 100%
  • Underrepresented Group 50%
  • Nanoscale 50%
  • Research Project 25%
  • Research Material 25%

• REU SITE: Collaborative Research: Nanoscale Detectives -- Elucidating the Structure and Dynamics of Hybrid Perovskite Systems

  Cahoon, J. J. (PI) & Huang, J. J. (CoPI)

  National Science Foundation

  15/9/21 → 31/8/24

  Project: Research Project

  • Perovskite Systems 100%
  • Underrepresented Group 100%
  • Nanoscale 100%
  • Research Project 50%
  • Research Material 50%

• Cellular and Molecular Mechanisms of Behavioral Dysfunction in a Zebrafish Model of CHARGE Syndrome

  Marsden, K. C. (PI)

  National Institute of Neurological Disorders and Stroke

  10/9/21 → 28/2/23

  Project: Research Project

  • Behavioral Dysfunction 100%
  • Cellular Mechanisms 100%
  • Zebrafish Model 100%
  • Illumination 100%
  • Proteomics 100%

• A cluster randomized trial to improve adolescent bicycling safety

  Hamann, C. C. (PI)

  Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institute of Child Health and Human Development

  9/9/21 → 31/8/24

  Project: Research Project

  • Cluster Randomized Trial 75%
  • Safety Education 75%
  • Parent Training 30%
  • Self-Efficacy 21%
  • Self-efficacy 20%

• Hatchable Solid State Transformer Rectifier Design through System Co-Optimization

  Lewis, P. P. (PI)

  U.S. Navy

  8/9/21 → 15/3/22

  Project: Research Project

  • 3D Rendering 22%
  • Transformer Design 11%
  • Power Infrastructure 11%
  • High Voltage Transmission Line 11%
  • Ship Power 11%

• UNLIMITED -OMICS APPLICATIONS THROUGH HIGH-RESOLUTION, SUB-CELLULAR PRECISION SAMPLE ISOLATION AND IMAGING

  Whitehill, J. J. (PI)

  National Institute of Food and Agriculture

  1/9/21 → 31/8/23

  Project: Research Project

  • Biological Sciences 100%
  • Sample Isolation 50%
  • High-resolution 50%
  • Omics 50%
  • USDA 33%

• Selective delivery of superoxide dismutase and catalase for restenosis prevention

  Cartaya, A. A. (PI)

  National Heart, Lung, and Blood Institute

  1/9/21 → 31/8/23

  Project: Research Project

  • Catalase 100%
  • Selective Delivery 50%
  • Restenosis 50%
  • Chapel Hill 12%
  • Arterial Surgery 12%

• Real-Time Bronchoscope Localization Using Machine Learning To Improve Lung Cancer Diagnosis

  Fried, I. (PI)

  National Cancer Institute

  1/9/21 → 31/8/24

  Project: Research Project

  • Lung Cancer Screening 100%
  • Bronchoscope 100%
  • Early Lung Cancer Diagnosis 25%
  • Built-in Camera 25%
  • Procedural 16%

• Planning Grant: Engineering Research Center for Green and Climate Resilient Built Environments (Green CRiB)

  Amassian, A. A. (PI), Long, T. A. (CoPI), Stingelin, N. N. (CoPI), Mcgehee, M. M. D. (CoPI) & Grubert, E. E. (CoPI)

  National Science Foundation

  1/9/21 → 31/8/23

  Project: Research Project

  • Engineering Research 50%
  • Indoor Temperature 25%
  • Problem Solver 14%
  • Human Comfort 14%
  • Window Glass 12%

• Collaborative Center to Develop Improved Diagnostic and Therapeutic Approaches to Endometriosis

  Young, S. S. L. (PI), Jeong, J.-W. J. (CoPI), Cox, L. L. A. (CoPI), Dasouki Abu-alnadi, N. N. (CoPI), Slayden, O. O. D. (CoPI), Cox, L. A. (CoPI), Jeong, J.-W. (CoPI) & Slayden, O. D. (CoPI)

  1/9/21 → 31/7/24

  Project: Research Project

  • Diagnostic Approach 100%
  • Endometriosis 100%
  • Sirtuin 1 71%
  • Diseases 42%
  • Overexpression 33%

• Catalyst Project: Biology Program Enhancement Through Education and Research in the Ecological Sciences

  Carr, T. T. (PI) & Melton, M. A. (CoPI)

  National Science Foundation

  1/9/21 → 31/8/23

  Project: Research Project

  • Ecological Science 100%
  • Science, Technology, Engineering and Mathematics 100%
  • Mathematics Education 33%
  • Augustine of Hippo 25%
  • Academic Retention 16%

• Clonal analysis of gliogenesis in the cerebral cortex

  Ghashghaei, H. T. (PI)

  National Institute of Neurological Disorders and Stroke

  1/9/21 → 31/8/22

  Project: Research Project

  • Gliogenesis 50%
  • Cerebral Cortex 50%
  • Comprehensive Map 16%
  • Healthy Development 16%
  • Tracing Technique 16%

• Synthetic matrices for studies on trophoblast differentiation in 3D culture

  Rao, B. M. (PI)

  National Institute of Child Health and Human Development

  1/9/21 → 31/8/23

  Project: Research Project

  • Synthetic Matrix 100%
  • Trophoblast 100%
  • Cytotrophoblast 77%
  • Trophoblast Invasion 44%
  • Placenta 31%

• NSF Postdoctoral Fellowship in Biology FY 2021: Elucidating the mechanism by which Taf14 links metabolic flux to gene transcription

  Lundy, T. T. A. (PI)

  National Science Foundation

  1/9/21 → 31/8/23

  Project: Research Project

  • Taf14 100%
  • Metabolic Flux 100%
  • Genetic Transcription 100%
  • Gene Transcription 50%
  • Postdoctoral Fellowship 50%

• Collaborative Research: Propagation, Evolution and Rotation in Linear Storms (PERiLS)

  Parker, M. M. D. (PI)

  National Science Foundation

  1/9/21 → 31/8/24

  Project: Research Project

  • United States of America 100%
  • Severe Weather 33%
  • Substorm 16%
  • Storm Environments 15%
  • Severe Winds 15%

• White Dwarf Stars Under the Influence of Planets

  Clemens, J. J. C. (PI)

  National Science Foundation

  1/9/21 → 31/8/24

  Project: Research Project

  • White Dwarf 100%
  • White Dwarfs 50%
  • Stellar Evolution 28%
  • Galactic 14%
  • Electromagnetic Interaction 14%

• MAARCO – Multi-terrain Amphibious ARCtic ExplOrer

  Mazzoleni, A. A. P. (PI) & Bryant, M. M. J. (CoPI)

  National Science Foundation

  1/9/21 → 31/8/24

  Project: Research Project

  • Terrain Conditions 60%
  • Robot 50%
  • Propulsion System 40%
  • Optimization Framework 40%
  • Robotics Challenge 20%

• How Do Unrepresentative College Grades Shape Race and Gender Gaps in the STEM Pipeline?

  Klasik, D. D. (PI), Hutt, E. E. (CoPI) & Sartain, L. L. (CoPI)

  National Science Foundation

  1/9/21 → 31/8/24

  Project: Research Project

  • Race Gap 100%
  • Science, Technology, Engineering and Mathematics 100%
  • Race-ethnicity 33%
  • Student Trajectories 33%
  • Grade Change 33%

• Comparative Toxicogenomics Database (CTD)

  Mattingly, C. J. (PI) & Davis, A. P. (CoPI)

  National Institute of Environmental Health Sciences

  1/9/21 → 30/6/24

  Project: Research Project

  • Disease 83%
  • Chemical Action 13%
  • Association Mechanism 13%
  • Network Exposure 13%
  • Code Design 13%

• FOOD ANIMAL RESIDUE AVOIDANCE DATABANK (FARAD)

  Jaberi-douraki, M. (PI)

  National Institute of Food and Agriculture

  1/9/21 → 31/8/23

  Project: Research Project

  • Animal Residues 100%
  • Maximum Residue Limit 50%
  • Animal-Based Food 50%
  • Transponder 25%
  • Retrieval System 20%

• Collaborative Research: Holocene and Late Pleistocene Stream Deposition in the McMurdo Dry Valleys, Antarctica as a Proxy for Glacial Meltwater and Paleoclimate

  Dewitt, R. R. (PI)

  National Science Foundation

  1/9/21 → 31/8/24

  Project: Research Project

  • Alluvial Fan 100%
  • Meltwater 83%
  • Glacier 50%
  • Fluvial Deposition 50%
  • Climate Change 37%

• Post translational modifications tune cardiac myosin

  Nesmelov, Y. (PI)

  National Heart, Lung, and Blood Institute

  1/9/21 → 31/8/24

  Project: Research Project

  • Posttranslational Modification 50%
  • Human Cardiac Myosin 44%
  • In Vitro Motility Assay 22%
  • Reversible Switching 11%
  • Transient Kinetics 11%

• Collaborative Research: Holocene and Late Pleistocene Stream Deposition in the McMurdo Dry Valleys, Antarctica as a Proxy for Glacial Meltwater and Paleoclimate

  Swanger, K. K. M. (PI)

  National Science Foundation

  1/9/21 → 31/8/24

  Project: Research Project

  • Alluvial Fan 100%
  • Meltwater 83%
  • Fluvial Deposition 50%
  • Climate Change 37%
  • Meltwater Flow 33%

• CCI Phase 1: NSF Center for Quantum Electrodynamics for Selective Transformations (QuEST)

  Krauss, T. D. (PI)

  National Science Foundation

  1/9/21 → 31/8/24

  Project: Research Project

  • Innovation Stages 100%
  • Selective Transformation 100%
  • Chemical Innovations 100%
  • Quantum Electrodynamics 100%
  • Polariton 30%

• Planning Grant: Engineering Research Center for Integrated Systems Operations and Planning of a Carbon Neutral Electric Grid

  Chowdhury, B. B. H. (PI), Tolone, W. W. J. (CoPI), Kamalasadan, S. S. (CoPI), Enslin, J. J. H. (CoPI) & Lu, N. N. (CoPI)

  National Science Foundation

  1/9/21 → 31/8/22

  Project: Research Project

  • Systems Planning 100%
  • System Operation 100%
  • Digital Twin 100%
  • Research Centre 100%
  • Technology Integration 66%

• Linking PFAS exposure to thyroid disruption and innate immunity

  Yoder, J. J. A. (PI)

  National Institute of Environmental Health Sciences

  16/8/21 → 31/7/23

  Project: Research Project

  • Polyfluoroalkyl Substances 66%
  • Cell Function 50%
  • Cell Line 25%
  • Hormone Determination 16%
  • Natural Killer Cell 16%

• Collaborative Research: Visualizing statistical force networks in colloidal materials far-from-equilibrium

  Hsiao, L. C. (PI)

  National Science Foundation

  15/8/21 → 31/7/24

  Project: Research Project

  • Dense Suspension 100%
  • Particle Interaction 100%
  • Fluid Dynamics 100%
  • Stress Propagation 100%
  • High Resolution 100%

• DISES: Influence of Community Forestry on the Dynamics of the Integrated Socio-Environmental Systems

  Song, C. C. (PI), Bilsborrow, R. E. (CoPI), Band, L. L. E. (CoPI), Sills, E. E. O. (CoPI) & Parajuli, R. R. (CoPI)

  National Science Foundation

  15/8/21 → 31/7/24

  Project: Research Project

  • Nepal 30%
  • Forest Management Practices 10%
  • Ecosystem Goods 10%
  • Hydrological Data 10%
  • Land Use 10%

• Collaborative Research: Analysis and Control in Multi-Scale Interface Coupling between Deformable Porous Media and Lumped Hydraulic Circuits

  Bociu, L. L. V. (PI)

  National Science Foundation

  15/8/21 → 31/7/24

  Project: Research Project

  • Deformable Porous Media 100%
  • Blood Pressure 100%
  • Glaucoma 66%
  • Glaucoma Patients 66%
  • Blood Flow 50%

• Mechanics of Granular Materials: Rigidity, Nonlocality, and Activated Failure

  Daniels, K. K. E. (PI)

  National Science Foundation

  15/8/21 → 31/7/24

  Project: Research Project

  • Mechanics of Granular Materials 100%
  • Historically Marginalized Groups 50%
  • Statistical Physics 25%
  • Edge Physics 25%
  • Mohr-Coulomb Failure 25%

• Relaxation of Slow Glassy Interphases in Polymeric Systems

  Simon, S. S. L. (PI)

  National Science Foundation

  15/8/21 → 30/6/24

  Project: Research Project

  • Semicrystalline Polymers 66%
  • Nanoparticle 66%
  • Nanostructured Materials 50%
  • Nanomaterial 50%
  • Structural Recovery 33%

• Building reconfigurable photonic materials and devices by light-guided self-assembly of nanoparticles

  Yan, Z. Z. (PI)

  National Science Foundation

  15/8/21 → 31/7/24

  Project: Research Project

  • Photonic Materials 100%
  • Optical Matter 80%
  • Optical Binding 60%
  • Nanoparticles 50%
  • Nanoparticle 50%

• Collaborative Research: Analysis and Control in Multi-Scale Interface Coupling between Deformable Porous Media and Lumped Hydraulic Circuits

  Guidoboni, G. G. (PI)

  National Science Foundation

  15/8/21 → 31/7/24

  Project: Research Project

  • Deformable Porous Media 100%
  • Glaucoma 66%
  • Glaucoma Patients 66%
  • Intraocular Pressure 50%
  • Biot Model 33%

• Early Life Phthalate Exposures in Relation to Structural and Functional Brain Development

  Engel, S. M. (PI) & Lin, W. W. (CoPI)

  National Institute of Environmental Health Sciences

  13/8/21 → 31/5/23

  Project: Research Project

  • Phthalate Exposure 100%
  • Structural Brain Development 100%
  • Phthalates 100%
  • Brain Development 100%
  • Brain Imaging 25%

• Non-invasive analysis of methylated cell free DNA in necrotizing enterocolitis

  Good, M. M. L. (PI) & Peters, D. D. G. (CoPI)

  12/8/21 → 31/5/24

  Project: Research Project

  • Cell-free DNA (cfDNA) 100%
  • Epigenetic Mechanism 100%
  • Mortality Rate 100%
  • DNA Methylation 100%
  • Cell Free DNA 100%

• A multimodal intervention to improve manual dexterity in subacute stroke survivors

  Kamper, D. (PI)

  National Institute of Child Health and Human Development

  10/8/21 → 31/7/23

  Project: Research Project

  • Apoplexy 100%
  • Keyboard 66%
  • Hand Exoskeleton 50%
  • Training Session 37%
  • Exoskeleton 37%

• Exploring the consequences of food insecurity and harnessing the power of peer navigation and mHealth to reduce food insecurity and cardiometabolic comorbidities among persons with HIV

  Rhodes, S. S. D. (PI) & Morse, C. C. (CoPI)

  National Institute of Nursing Research

  4/8/21 → 30/6/24

  Project: Research Project

  • Peer Navigation 100%
  • Food Insecure 40%
  • Food Secure 20%
  • Bilingual 13%
  • Insulin Sensitivity 6%

• Indoor and outdoor light at night: Associations with sleep and breast cancer

  Sweeney, M. R. (PI)

  National Institute of Environmental Health Sciences

  1/8/21 → 31/7/22

  Project: Research Project

  • Confidence Interval 100%
  • Sleep Quality 100%
  • Fine Particulate Matter 50%
  • Disruptions 50%
  • Poor Quality 50%

• Excellence in Research: Predicting computations that lead to a stable perception of object lightness under spectral variabilities of the visual scene

  Singh, V. V. (PI)

  National Science Foundation

  1/8/21 → 31/7/24

  Project: Research Project

  • Spectral Variability 100%
  • Human Participant 100%
  • Background Objects 50%
  • Excellence in Research 50%
  • Lightness Perception 50%