UNC Kenan-Flagler

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  Understanding the Contribution of Endothelial Lipid Droplet Metabolism in Cardiovascular Diseases

  Kim, B. B. (PI) & Kim, B. B. (CoPI)

  9/9/22 → 9/1/23

  Project: Research Project

  • Lipid Droplets 100%
  • Cardiovascular Disease 100%
  • Lipid Droplet 100%
  • Metabolic Pathway 100%
  • Triacylglycerol Lipase 35%

• CAMELLIA Cohort: A longitudinal study to understand sexual health and prevention among women in Alabama

  Elopre, L. L. E. (PI) & Matthews, L. L. T. (CoPI)

  Eunice Kennedy Shriver National Institute of Child Health and Human Development

  8/9/22 → 31/8/24

  Project: Research Project

  • Infection 100%
  • HIV 100%
  • Deep South 66%
  • Prevention Tool 50%
  • Communities of Color 50%

• Leveraging routinely collected health data to improve early identification of autism and co-occurring conditions

  Goldstein, B. A. (PI)

  Eunice Kennedy Shriver National Institute of Child Health and Human Development

  6/9/22 → 31/8/23

  Project: Research Project

  • Autism 100%
  • Early Identification 100%
  • Primary Medical Care 100%
  • Pervasive Developmental Disorder 100%
  • Autism Prediction 40%

• Studies of optical and chemical properties of aged and fresh biomass burning absorbing aerosols for climate models

  Bililign, S. S. (PI) & Fiddler, M. M. (CoPI)

  Biological and Environmental Research

  1/9/22 → 29/2/24

  Project: Research Project

  • Atmospherics 100%
  • Optical Properties 100%
  • Biomass Burning 100%
  • Professional Networks 66%
  • Atmospheric Science 66%

• Building research capacity in Southern Appalachian mountain wetlands

  Wilcox, J. J. (PI)

  Biological and Environmental Research

  1/9/22 → 30/4/24

  Project: Research Project

  • Mountain Wetlands 100%
  • Research Capacity Building 50%
  • Principal Investigators 50%
  • Principal Investigator 28%
  • Stormwater Management 25%

• Research Capacity Core

  Richardson, M. M. R. (PI)

  National Institute on Minority Health and Health Disparities

  1/9/22 → 31/8/23

  Project: Research Project

  • Research Capacity 100%
  • North Carolina 66%
  • Health Disparities Research 55%
  • Behavioral Health 44%
  • Health Communication 40%

• Preventing Age-Associated Oocyte Aneuploidy: Mechanisms Behind the Drosophila melanogaster Centromere Effect

  Pazhayam, N. N. M. (PI)

  National Institute on Aging

  1/9/22 → 31/8/24

  Project: Research Project

  • Centromere Effect 66%
  • Drosophila Melanogaster 66%
  • Centromere 66%
  • Heterochromatin 56%
  • Pericentromeric Heterochromatin 40%

• The Role of CSF Dynamics in Infant Brain and Behavioral Development in Down Syndrome and Related Neurodevelopmental Disorders

  Garic, D. D. (PI)

  Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institute of Child Health and Human Development

  1/9/22 → 31/8/24

  Project: Research Project

  • Cerebrospinal Fluid Dynamics 100%
  • Behavioral Development 66%
  • Neurodevelopmental Disorders 66%
  • Disease 66%
  • Cerebrospinal Fluid Flow 25%

• Fibrin-CAR-T cells therapies to enhance efficacy in glioblastoma treatments

  Ogunnaike, E. E. (PI)

  National Institute of Neurological Disorders and Stroke

  1/9/22 → 31/8/24

  Project: Research Project

  • Fibrin 100%
  • Glioblastoma Therapy 100%
  • Chimeric Antigen Receptor T-cell Therapy 66%
  • Chimeric Antigen Receptor T Cells (CAR-T) 66%
  • Glioblastoma 50%

• EASTERN BAND OF CHEROKEE INDIANS FEDERALLY RECOGNIZED TRIBES EXTENSION PROGRAM 2022

  Walker, R. R. R. R. (PI)

  National Institute of Food and Agriculture

  1/9/22 → 31/8/23

  Project: Research Project

  • Extension Program 100%
  • Extension Programs 100%
  • Natural Resources 100%
  • Traditional Foods 100%
  • Land Classification 50%

• Intravesical Immunotherapy of Spontaneous Canine Invasive Urothelial Carcinoma

  Zaharoff, D. D. (PI) & Hess, P. P. R. (CoPI)

  National Cancer Institute

  1/9/22 → 31/8/24

  Project: Research Project

  • Transitional Cell Carcinoma 100%
  • Chitosan 100%
  • Invasive Urothelial Carcinoma 100%
  • Immunotherapy 66%
  • Interleukin 12 50%

• Approaches and Outcomes of Shared Decision-making and Patient Centered Care Delivery in Barrett's Esophagus

  Eluri, S. S. (PI)

  National Institute of Diabetes and Digestive and Kidney Diseases

  1/9/22 → 31/5/24

  Project: Research Project

  • Shared Decision Making 100%
  • Patient-centered Care 100%
  • Patient-Reported Outcome 100%
  • Barrett's Esophagus 66%
  • Care Delivery 66%

• Monitoring antimicrobial resistance (AMR) in enteric pathogens isolated from retail meats and seafoods in North Carolina

  Thakur, S. S. (PI)

  U.S. Food and Drug Administration

  1/9/22 → 31/8/24

  Project: Research Project

  • Seafood 100%
  • Retail Meat 66%
  • Enteric Pathogens 66%
  • North Carolina 66%
  • Antimicrobial Resistance 66%

• FOOD ANIMAL RESIDUE AVOIDANCE DATABANK (FARAD)

  Jaberi-douraki, M. (PI)

  National Institute of Food and Agriculture

  1/9/22 → 31/8/23

  Project: Research Project

  • Animal Residues 100%
  • Food Animals 100%
  • University of Kansas 50%
  • Veterinary Medicine 33%
  • University of Virginia 16%

• Automated Data Collection on Antimicrobial Use in Dogs and Cats in a Tertiary Hospital and Private Practices

  Lanzas, C. (PI)

  U.S. Food and Drug Administration

  1/9/22 → 31/8/24

  Project: Research Project

  • Automated Data Collection 100%
  • Hospital Practice 100%
  • Cat 100%
  • Private Practice 66%
  • Information Management System 66%

• Prenatal stress and diet, and the fetal epigenome

  Hoyo, C. C. (PI)

  National Institute on Minority Health and Health Disparities

  1/9/22 → 31/3/24

  Project: Research Project

  • Methylation 100%
  • Epigenome 100%
  • Prenatal Diet 100%
  • Prenatal Stress 100%
  • Epigenetics 75%

• Nutritional Regulation of Luteinizing Hormone Secretion

  Nestor, C. C. C. (PI)

  Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institute of Child Health and Human Development

  1/9/22 → 31/7/24

  Project: Research Project

  • Gonadotropins 100%
  • Luteinizing Hormone Secretion 100%
  • Food Regulation 100%
  • Gonadotropin 100%
  • Kisspeptin Neurons 45%

• CC* Data Storage: Flexible Affordable Scalable Technology for Research Storage (FAST-Research Storage)

  Futhey, T. (CoPI), Boyer, D. (CoPI), Futhey, T. (CoPI), Bartesaghi, A. (PI) & Bartesaghi, A. (CoPI)

  National Science Foundation

  1/9/22 → 31/8/24

  Project: Research Project

  • Scalable Technology 100%
  • Storage Service 100%
  • Storage Model 50%
  • Storage Requirement 50%
  • Data Retention 50%

• The Human Lung BioMolecular Multi-Scale Atlas Program (HuBMAP-Lung)

  Pryhuber, G. G. S. (PI)

  National Heart, Lung, and Blood Institute

  1/9/22 → 31/8/24

  Project: Research Project

  • Gene Expression 100%
  • Transcriptomics 100%
  • RNA Sequence 100%
  • Cell Function 100%
  • Lipid 100%

• Peer Support for Lowering Blood Pressure among Adolescents: A Pilot, Randomized Controlled Trial

  Hardy, S. S. T. (PI)

  National Heart, Lung, and Blood Institute

  1/9/22 → 31/8/24

  Project: Research Project

  • Blood Pressure Lowering 100%
  • Blood Pressure 100%
  • Epidemiology 53%
  • Adolescent 50%
  • Department of Medicine 40%

• The Role of Kaiso as a predictive breast cancer biomarker in Africa and across the African Diaspora

  Gardner, K. K. L. (PI)

  National Cancer Institute

  1/9/22 → 31/8/24

  Project: Research Project

  • Breast Cancer Biomarkers 100%
  • Africa 100%
  • African Diaspora 100%
  • Subcellular Localization 100%
  • Tumor Marker 100%

• Adapting a point of use test card, the chemoPAD, for protecting chemotherapy drug quality in sub-Saharan Africa

  Lieberman, M. M. (PI)

  National Cancer Institute

  23/8/22 → 31/7/24

  Project: Research Project

  • Drug Quality 100%
  • Sub-Saharan Africa 66%
  • Mobile Phone Application 60%
  • Regulatory Capacity 40%
  • Malawi 40%

• Investigating SARS-CoV-2 transmission dynamics in jails to address the COVID-19 public health emergency

  Levintow, S. S. N. (PI)

  National Institute of Allergy and Infectious Diseases

  22/8/22 → 31/7/24

  Project: Research Project

  • Public Health Emergency 100%
  • COVID-19 Mortality 100%
  • COVID-19 100%
  • Prison 50%
  • Infectious Diseases 50%

• Computational tools and quantitative analyses of genome structure evolution

  Guerrero, R. R. F. (PI)

  National Institute of General Medical Sciences

  18/8/22 → 30/6/24

  Project: Research Project

  • Genome Structure Evolution 100%
  • Sex Chromosomes 66%
  • Computational Tools 66%
  • Genomic Structure 66%
  • Quantitative Technique 66%

• Novel Deep Learning Tools for Clinical Decision Support in Postoperative Pain Management

  Zou, B. (PI)

  U.S. National Library of Medicine

  16/8/22 → 31/7/24

  Project: Research Project

  • Deep Learning System 100%
  • Causal Mechanism 100%
  • clinical decision support 100%
  • Patient Needs 66%
  • Deep Learning 66%

• Tobacco-based Sustainable Squalene for Novel Vaccine Adjuvant Emulsions

  Gorman, C. C. R. (PI)

  National Institute of Allergy and Infectious Diseases

  15/8/22 → 31/7/23

  Project: Research Project

  • Vaccine Adjuvant 100%
  • Squalene 100%
  • Emulsion 50%
  • Tobacco 50%
  • Vaccine Efficacy 50%

• Zeiss LSM 980 Confocal Microscope

  Itano, M. M. S. (PI)

  NIH Office of the Director

  15/8/22 → 14/8/23

  Project: Research Project

  • Zeiss 100%
  • Confocal Microscope 100%
  • Confocal Microscopy 100%
  • Neuroscience 75%
  • Molecular Imaging 66%

• Catalyst Project: Age and temperature-dependent millimeter-wave charge carrier dynamics in hybrid perovskite films

  Roy, B. (PI)

  National Science Foundation

  15/8/22 → 31/7/24

  Project: Research Project

  • Perovskite Film 100%
  • Liquid Film 100%
  • Charge Carrier 100%
  • Millimeter Wave 100%
  • Time-resolved Microwave Conductivity 50%

• Systems biology of quiescence entry

  Argüello-miranda, O. O. (PI)

  National Institute of General Medical Sciences

  3/8/22 → 31/7/24

  Project: Research Project

  • Cell Cycle 66%
  • Systems Biology 66%
  • Cellular Quiescence 50%
  • Biochemical Techniques 33%
  • Leadership 33%

• Activity-Enhanced Self-Assembly of Colloidal-Based Materials

  Klotsa, D. D. (PI)

  Basic Energy Sciences

  1/8/22 → 31/1/25

  Project: Research Project

  • Self-assembly 100%
  • Assembly Process 100%
  • Active Particles 100%
  • Colloids 50%
  • Local Temperature 50%

• Super Resolution STED Microscopy at UNC

  Gupton, S. S. (PI)

  NIH Office of the Director

  1/8/22 → 31/7/23

  Project: Research Project

  • Super-resolution STED Microscopy 100%
  • Stimulated Emission Depletion 66%
  • Cytotechnology 50%
  • Medicine 50%
  • Biomedical Research 50%

• High Resolution Fluorescence Imaging of Dense Brain Regions with Dual Selective Plane Illumination Microscopy

  Itano, M. M. S. (PI)

  National Institute of Mental Health

  1/8/22 → 31/7/23

  Project: Research Project

  • Selective Plane Illumination Microscopy 100%
  • Brain Tissue 100%
  • Fluorescence Imaging 50%
  • High-resolution 50%
  • Brain Regions 50%

• Drug Retention and Tumor Distribution of Polymeric Micelles for Cancer Therapy

  Ramsey, J. J. D. (PI)

  National Cancer Institute

  1/8/22 → 31/7/24

  Project: Research Project

  • Polymeric Micelles 100%
  • Tumor Distribution 100%
  • Cancer Therapy 66%
  • Malignant Neoplasm 66%
  • Neoplasm 66%

• Collaborative Research: Mathematical and Experimental Analysis of Competitive and Predator-Prey Models: Conditional Dispersal on Patches to Landscapes

  Shivaji, R. R. (PI)

  National Science Foundation

  1/8/22 → 31/7/23

  Project: Research Project

  • Density Dependent Emigration 100%
  • Shared Predator 75%
  • Life-history Trade-offs 75%
  • Interspecific Competition 50%
  • Landscape Level 37%

• Upgrade of Bruker Time-domain EPR Spectrometer

  Smirnov, A. A. I. (PI)

  NIH Office of the Director

  1/8/22 → 31/7/23

  Project: Research Project

  • Q-band 100%
  • Electron Paramagnetic Resonance Spectrometer 100%
  • Bruker 50%
  • Arbitrary Waveform Generator 50%
  • Distance Range 50%

• PIPP Phase I: Real-time Analytics to Monitor and Predict Emerging Plant Disease

  Ristaino, J. B. (CoPI), Carbone, I. (CoPI), Delborne, J. A. (CoPI), Delborne, J. A. (CoPI) & Ristaino, J. B. (PI)

  National Science Foundation

  1/8/22 → 31/1/25

  Project: Research Project

  • Pandemic Prevention 100%
  • Predictive Intelligence 100%
  • Plant Disease 100%
  • Emerging Plant Disease 50%
  • Pandemic Preparedness 22%

• The Don S. Fredrickson Lipid Research Conference

  Graf, G. A. (PI)

  National Heart, Lung, and Blood Institute

  1/8/22 → 31/7/23

  Project: Research Project

  • Lipoprotein Metabolism 100%
  • 6 Diazo 5 Oxonorleucine 100%
  • Disease 75%
  • Diabetes 50%
  • Lipids Research 50%

• Light-Activated Silver Nanoparticles to Eliminate Antibiotic Resistant Bacteria and Genes

  Vivero-escoto, J. J. L. (PI)

  National Institute of General Medical Sciences

  1/8/22 → 31/7/24

  Project: Research Project

  • Antibiotic-resistant Bacteria 100%
  • Antibiotic Resistance Genes 100%
  • Light Activation 100%
  • Silver Nanoparticle 100%
  • Antibiotic Resistance 59%

• Stimuli-responsive mucin1-specific nanoparticles for efficacious combinatorial chemotherapy of pancreatic ductal adenocarcinoma

  Vivero-escoto, J. J. L. (PI)

  National Cancer Institute

  1/8/22 → 31/7/24

  Project: Research Project

  • Stimuli-responsive 100%
  • Gemcitabine Plus Cisplatin 100%
  • Pancreas Adenocarcinoma 100%
  • Cisplatin 85%
  • Nanoparticle 66%

• SPLENDOR-NC Supplement to Develop the BRIDGES Consortium Brand Guide and Website

  Mayer-davis, E. J. (PI), Ongeri, E. E. M. (CoPI) & Shaikh, S. S. R. (CoPI)

  National Institute of Diabetes and Digestive and Kidney Diseases

  15/7/22 → 31/5/24

  Project: Research Project

  • North Carolina 95%
  • Nutrition Research 76%
  • Career Development 76%
  • Obesity Research 76%
  • Diverse Faculty 66%

• Enhanced intratympanic delivery of therapeutics to treat and prevent hearing loss using nanovesicles in the porcine model

  Moatti, A. A. (PI)

  National Institute on Deafness and Other Communication Disorders

  15/7/22 → 30/6/24

  Project: Research Project

  • Round Window Membrane 100%
  • Hearing Impairment 100%
  • Pig 100%
  • Porcine Model 66%
  • Porcine 30%

• LUMICKS C-TRAP

  Schmidt, C. C. F. (PI)

  NIH Office of the Director

  15/7/22 → 14/7/23

  Project: Research Project

  • Confocal Microscopy 100%
  • Cytotechnology 100%
  • Cell Adhesion 100%
  • Optical Tweezer 100%
  • Medicine 100%

• Single cell, genome wide dissection of dynamic transcription factor regulation

  Caywood, L. L. (PI)

  National Cancer Institute

  11/7/22 → 10/7/24

  Project: Research Project

  • Single-cell Genomics 100%
  • Transcription Factor 100%
  • Single-cell RNA Sequencing (scRNA-seq) 100%
  • Dynamics 100%
  • Transcription Factors 100%

• Characterizing Gene-Environment Interactions that Affect Individual Susceptibility to an Expanding Chemical Exposome

  Wright, F. F. A. (PI) & Reif, D. M. (CoPI)

  National Institute of Environmental Health Sciences

  8/7/22 → 30/4/24

  Project: Research Project

  • Genotype Environment Interaction 100%
  • Exposome 100%
  • Differential Susceptibility 100%
  • Gene-Environment Interaction 66%
  • Chemical Exposure 50%

• Establishing Foundations to Develop a Treatment Decision Aid for Patients Hospitalized with Unexpected End-Stage Kidney Disease: A Community Engaged Approach

  Urbanski, M. M. (PI)

  National Institute of Diabetes and Digestive and Kidney Diseases

  1/7/22 → 30/6/23

  Project: Research Project

  • Kidney Replacement Therapy 100%
  • Treatment Decisions 50%
  • Decision Aid 50%
  • End Stage Renal Disease 50%
  • Therapy Decision 21%

• UNC-CH Training Program in Health Services Research

  Holmes, G. G. M. (PI)

  Agency for Healthcare Research and Quality

  1/7/22 → 30/6/24

  Project: Research Project

  • Doctor of Philosophy 66%
  • Health Services Research 66%
  • Training Program 33%
  • Family Practice 19%
  • Health Behavior 16%

• Novel Sequencing Based Diagnostics for Leukemia in Low Resource Settings

  Alexander, T. T. B. (PI) & Wang, J. J. R. (CoPI)

  National Cancer Institute

  1/7/22 → 30/6/24

  Project: Research Project

  • Direct RNA Nanopore Sequencing 100%
  • Leukemia 66%
  • Low-resource Settings 66%
  • RNA Sequence 66%
  • Health Care Cost 33%

• High Throughput Clonal Analyses of Gliogenesis in Neocortical and Paleocortical areas of the Mouse Brain

  Ghashghaei, H. T. (PI) & Greenbaum, A. A. (CoPI)

  National Institute of Neurological Disorders and Stroke

  1/7/22 → 30/6/24

  Project: Research Project

  • Neocortical 100%
  • Gliogenesis 100%
  • Neural Stem Cell 100%
  • High-throughput 50%
  • Clonal Analysis 50%

• Enhance the surveillance of foodborne bacterial pathogens isolated from food and environmental samples using whole genome sequencing (WGS) to prevent foodborne outbreaks and promote public health

  Thakur, S. S. (PI)

  U.S. Food and Drug Administration

  1/7/22 → 30/6/24

  Project: Research Project

  • Foodborne Disease 66%
  • Public Health 66%
  • Whole Genome Sequencing 66%
  • Foodborne Outbreak 66%
  • Foodborne Pathogens 40%

• Matching and Data Integration

  Ma, Z. (PI)

  National Science Foundation

  1/7/22 → 31/10/23

  Project: Research Project

  • Data Integration 100%
  • Overlapping Features 100%
  • Human Resources 100%
  • University of North Carolina 50%
  • Data Communication 50%