UNC Kenan-Flagler

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• AUTOANTIBODIES TO ACTIVATED LYMPHOCYTES IN SLE

  Winfield, J. J. B. (CoPI) & Winfield, J. B. (PI)

  National Institute of Arthritis and Musculoskeletal and Skin Diseases

  1/4/92 → 31/3/96

  Project: Research Project

  • Activated Lymphocytes 100%
  • Autoantibodies 80%
  • Autoimmune Disease 18%
  • Lymphocytes 12%
  • Phosphatase 7%

• THE LABORATORIES FOR REPRODUCTIVE BIOLOGY

  French, F. F. S. (CoPI), French, F. S. (PI), O'brien, D. A. (CoPI), Ordronneau, P. (CoPI), Petrusz, P. (CoPI) & Wilson, E. M. (CoPI)

  National Institute of Child Health and Human Development

  1/8/85 → 31/3/96

  Project: Research Project

  • Reproductive Biology 100%
  • Administrative Services 25%
  • Histochemistry 25%
  • Recombinant DNA 25%
  • Radioimmunoassay 25%

• STEROL COMPONENTS OF YEAST

  Parks, L. W. (PI)

  National Institute of Diabetes and Digestive and Kidney Diseases

  1/9/86 → 31/3/96

  Project: Research Project

  • Sterols 100%
  • Sterol Metabolism 100%
  • Health Problems 25%
  • Organ Transplant 25%
  • Immunosuppressive Therapy 25%

• Modeling and Analysis of Global Vision for Operating Multiple Free-Ranging AGVs on the Factory Floor

  Luo, R. R. C. (PI)

  National Science Foundation

  1/10/92 → 31/3/96

  Project: Research Project

  • Free-range 100%
  • Global Vision 100%
  • Difference Image 100%
  • Transport Vehicle 100%
  • Software Implementation 100%

• HIV/AIDS--DEVELOPMENT OF CHILDRENS UNDERSTANDING

  Whitt, N. J. K. (PI)

  National Institute of Mental Health

  1/5/92 → 30/4/96

  Project: Research Project

  • Prevention Behavior 100%
  • Health Promotion 75%
  • Illness 75%
  • AIDS/HIV 75%
  • Maturation 50%

• NEURAL TUBE DEFECTS IN MICE

  Sadler, T. T. W. (CoPI) & Sadler, T. W. (PI)

  National Institute of Child Health and Human Development

  1/5/92 → 30/4/96

  Project: Research Project

  • Neural Tube Defect 100%
  • Neural Tube Defects 80%
  • Tail 64%
  • Cell Death 64%
  • Protein Binding 48%

• CISE Research Instrumentation: Analysis and Verification of Concurrent Systems

  Iyer, S. S. P. (PI), Tai, K.-C.K.-C. (CoPI), Cleaveland, W. R. W. R. (CoPI) & Vouk, M. A. (CoPI)

  National Science Foundation

  1/5/95 → 30/4/96

  Project: Research Project

  • Transmission Error 100%
  • Reachability 100%
  • Error Control 66%
  • Control Algorithm 50%
  • Symbolics 50%

• Quantum Transport in Silicon/Silicon-Germanium Nanostructures

  Washburn, S. S. (PI) & Ismail, K. K. E. (CoPI)

  National Science Foundation

  1/5/94 → 30/4/96

  Project: Research Project

  • Germanium Nanowire (GeNW) 100%
  • Quantum Transport 100%
  • Silicon-germanium Alloy 66%
  • Silicon-germanium 50%
  • Quantization (Signal Processing) 50%

• Mechanism of Protein Biosynthesis in Animal Mitochondria

  Spremulli, L. L. L. (PI)

  National Science Foundation

  1/5/92 → 30/4/96

  Project: Research Project

  • Initiator tRNA 33%
  • Cytoplasmic Inheritance 33%
  • Extranuclear Inheritance 25%
  • Initiation Complex 25%
  • Mitochondrial Protein 25%

• MHCRC-PSYCHOENDOCRINOLOGY: CHILDREN AND ADULTS

  Prange, A. A. J. (CoPI), Prange, A. J. (PI), Carson, S. W. (CoPI), Garbutt, J. C. (CoPI), Golden, R. N. (CoPI), Mason, G. A. (CoPI), Richardson, W. G. (CoPI) & Stern, R. A. (CoPI)

  National Institute of Mental Health

  1/6/85 → 31/5/96

  Project: Research Project

  • Metabolism 44%
  • Hypothyroidism 44%
  • Closed Head Injury 44%
  • Metabolic Pathway 44%
  • Alcoholism 44%

• CANCER EARLY DETECTION

  Kaluzny, A. A. D. (CoPI) & Kaluzny, A. D. (PI)

  National Cancer Institute

  1/6/91 → 31/5/96

  Project: Research Project

  • Office System 100%
  • North Carolina 91%
  • Primary Care Practice 66%
  • Preventive Care 66%
  • Geographic Region 33%

• Purchase of a Laser System for Photoinitiated Charge Transfer Studies

  Rillema, D. P. D. P. (PI)

  National Science Foundation

  15/6/94 → 31/5/96

  Project: Research Project

  • Chromophore 100%
  • Charge Transfer 50%
  • Transfer Research 50%
  • Solar Energy Conversion 50%
  • University of North Carolina 25%

• ADENO-ASSOCIATED VIRUS--EUKARYOTIC VIRAL VECTOR

  Samulski, R. J. (PI)

  National Institute of Diabetes and Digestive and Kidney Diseases

  1/6/90 → 31/5/96

  Project: Research Project

  • Virus Vector 100%
  • Adeno Associated Virus 100%
  • Infection 33%
  • Mixed Infection 22%
  • Helper Virus 22%

• CNS TRANSMITTERS AND METABOLITES IN ALCOHOL ADDICTION

  Myers, R. D. (PI)

  National Institute on Alcohol Abuse and Alcoholism

  27/9/85 → 30/6/96

  Project: Research Project

  • Hippocampus 100%
  • Receptor Antagonist 66%
  • Alcohol 66%
  • Transmitter 66%
  • Alcoholic Polyneuropathy 66%

• PATHOPHYSIOLOGY OF ANTIPHOSPHOLIPID AUTOANTIBODIES

  Roubey, R. R. A. (CoPI) & Roubey, R. A. (PI)

  National Institute of Arthritis and Musculoskeletal and Skin Diseases

  15/7/93 → 30/6/96

  Project: Research Project

  • Autoantibodies 100%
  • Pathophysiology 100%
  • Phospholipids 100%
  • Phospholipid 100%
  • Glycoprotein 45%

• CHILD SOCIALIZATION AND ONSET OF TOBACCO AND ALCOHOL USE

  Jackson, C. (CoPI)

  National Institute on Drug Abuse

  1/8/92 → 30/6/96

  Project: Research Project

  • Alcohol Use 100%
  • Child-onset 100%
  • Tobacco Use 100%
  • Alcohol Consumption 100%
  • Early Prevention Program 50%

• Dissertational Improvement: Polarization Sensitivity in Ophiuroids: The Structure and Ecological Function of a Diffuse Photic System

  Kier, W. W. M. (PI) & Johnsen, S. S. (CoPI)

  National Science Foundation

  15/7/94 → 30/6/96

  Project: Research Project

  • Sensory System 100%
  • Brittle Star 100%
  • Structure Function 50%
  • Ecological Function 50%
  • Endoskeleton 50%

• CRB: Species-centered Environmental Analysis for the Red- cockaded Woodpecker

  James, F. F. C. (PI)

  National Science Foundation

  1/7/92 → 30/6/96

  Project: Research Project

  • Red-cockaded Woodpecker 100%
  • Environmental Analysis 100%
  • Picoides borealis 33%
  • Endangered Species 33%
  • Foraging Habitat 25%

• Reliability of Real-Time Engineering Software

  Baugh, J. J. W. (PI)

  National Science Foundation

  15/7/92 → 30/6/96

  Project: Research Project

  • Fault Tolerance 100%
  • Static Verification 50%
  • Real-time Testing 50%
  • System Failure 50%
  • Runtime Support 50%

• A Classroom for the Integration of Computer Explorations into the Calculus Sequence

  Gale, S. S. L. (PI) & Atkinson, L. L. (CoPI)

  National Science Foundation

  1/7/94 → 30/6/96

  Project: Research Project

  • Class Session 66%
  • Matrix-assisted Pulsed Laser Evaporation (MAPLE) 66%
  • Macintosh 66%
  • Computer Algebra System 50%
  • Real-world Application 33%

• Liberal Democracy Measures 1980-1990

  Bollen, K. K. A. (PI)

  National Science Foundation

  1/5/92 → 30/6/96

  Project: Research Project

  • Liberal Democracy 100%
  • Democracy Index 100%
  • Democracy 100%
  • Random Error 20%
  • Democratic Development 20%

• NEURONAL AGING AND NEURODEGENERATIVE DISEASES

  Udom, C. E. (CoPI) & Udom, C. C. E. (PI)

  National Institute on Aging

  1/8/92 → 30/6/96

  Project: Research Project

  • Neurodegenerative Disorder 100%
  • Degenerative Disease 100%
  • Cyclic Adenosine Monophosphate 66%
  • Differentiated Neuroblastoma Cells 50%
  • Neurodegenerative Diseases 50%

• INSULINLIKE GROWTH FACTOR I--INFLAMMATORY BOWEL DISEASE

  Zimmermann, E. M. (PI) & Zimmermann, E. M. (CoPI)

  National Institute of Diabetes and Digestive and Kidney Diseases

  1/7/92 → 30/6/96

  Project: Research Project

  • Inflammatory Bowel Disease 100%
  • Growth Factor 59%
  • Peptidoglycan Polysaccharide 51%
  • Fibrinogen 50%
  • Insulin-like Growth factor-1 50%

• CLINICAL EVALUATION OF DIGITAL MAMMOGRAPHY

  Feig, S. A. (PI)

  National Cancer Institute

  30/9/93 → 30/6/96

  Project: Research Project

  • Clinical Evaluation 66%
  • Digital Mammography 66%
  • Mammogram 41%
  • Digital Mammogram 25%
  • University of North Carolina 25%

• Minority Institutions Infrastructure: Project RAISE

  Marshall, R. R. G. (PI) & Jones, E. (CoPI)

  National Science Foundation

  1/8/95 → 31/7/96

  Project: Research Project

  • Infrastructure Projects 100%
  • Long-range Planning 50%
  • Piedmont 50%
  • Undergraduate Institutions 50%
  • Infrastructure Program 50%

• CMOS IC Performance Enhancement Via Wave Pipelining

  Liu, W. W. (PI)

  National Science Foundation

  1/8/92 → 31/7/96

  Project: Research Project

  • CMOS IC 100%
  • Logic Circuit 50%
  • Digital System 50%
  • Computer Aided Design 50%
  • Logic Architecture 16%

• Upgrade Request for the Triangle Universities Electron Microprobe Facility

  Boudreau, A. A. E. (PI)

  National Science Foundation

  15/8/94 → 31/7/96

  Project: Research Project

  • Earth Science 50%
  • Earth Sciences 37%
  • Radiogenic Isotope 33%
  • Hafnium 33%
  • Laboratory Equipment 25%

• Dissertation Research: Evaluating the National Estuary Program: A Case Study of the Albemarle-Pamlico Estuarine Study

  Orbach, M. M. L. (PI)

  National Science Foundation

  1/8/95 → 31/7/96

  Project: Research Project

  • National Estuary Program 100%
  • Environmental Management 100%
  • Dissertation Research 50%
  • Albemarle 50%
  • Case Study 50%

• MECHANISM OF LARGE T ANTIGEN-INDUCED TUMORIGENESIS

  Van Dyke, T. A. (CoPI) & Van Dyke, T. A. (PI)

  National Cancer Institute

  1/8/92 → 31/7/96

  Project: Research Project

  • Choroid Plexus Epithelial Cells 100%
  • Choroid Plexus 100%
  • Carcinogenesis 87%
  • Transgenic Mice 50%
  • Scientific Environment 25%

• KINDLED SEIZURES AND VASOPRESSIN GENE REGULATION

  Greenwood, R. S. (PI)

  National Institute of Neurological Disorders and Stroke

  7/9/92 → 31/8/96

  Project: Research Project

  • Vasopressin 75%
  • Glutamate 56%
  • Cellular Pattern 50%
  • Hypothalamus 37%
  • Glutamate Receptor 37%

• OUTCOME OF ALZHEIMER'S SPECIAL CARE UNITS IN FOUR STATES

  Sloane, P. D. (PI)

  National Institute on Aging

  30/9/91 → 31/8/96

  Project: Research Project

  • Four States 100%
  • Special Care Unit 100%
  • Alzheimer 75%
  • Nursing Homes 22%
  • Nursing Home Care 22%

• IMMUNOGENIC EPITOPES OF HCV ENVELOPE PROTEINS

  Lemon, S. M. (PI)

  National Cancer Institute

  30/9/92 → 31/8/96

  Project: Research Project

  • Hepatitis C Virus 75%
  • Viral Protein 30%
  • Monoclonal Antibody 26%
  • Virus-like Particles 22%
  • Flow Cytometry 15%

• NEUROPHYSIOLOGICAL STUDIES OF RESPIRATORY CONTROL

  Eldridge, F. L. (CoPI) & Eldridge, F. L. (PI)

  National Heart, Lung, and Blood Institute

  1/9/88 → 31/8/96

  Project: Research Project

  • Central Command 100%
  • Phrenic 100%
  • Brainstem 100%
  • Medullary nucleus 50%
  • Output Variable 50%

• Upgrading of Electron Microprobe and X-ray Fluorescence Spectrometer Analytical Instruments: Petrologic, Geochemicaland Mineralogic Research at North Carolina State

  Fodor, R. R. V. (PI)

  National Science Foundation

  1/9/93 → 31/8/96

  Project: Research Project

  • X-Ray Fluorescence Spectroscopy 100%
  • North Carolina 50%
  • X-ray Fluorescence 33%
  • Earth Science 16%
  • Atmospheric Science 16%

• Acquisition of a Photon-Counting Video Imaging System

  Curtis, S. S. E. (PI), Thompson, W. F. (CoPI) & Hanley-bowdoin, L. L. K. (CoPI)

  National Science Foundation

  1/3/93 → 31/8/96

  Project: Research Project

  • Gene Expression 100%
  • Photon Counting 50%
  • Imaging Systems 50%
  • Isolation Procedure 50%
  • Trans-acting Regulator 33%

• BIOLOGICAL ACTIVITY OF SALIVARY NEUROLEUKIN

  Bristow, C. L. (PI)

  National Institute of Dental and Craniofacial Research

  15/9/94 → 14/9/96

  Project: Research Project

  • Biological Activity 66%
  • Human Immunodeficiency Virus 17%
  • Monomer 14%
  • Polyethylene Glycol 7%
  • Intravenous Immunoglobulin 7%

• INFLUENCE OF BLOOD-NERVE BARRIER ALTERATIONS ON TOXIC NEUROPATHIES

  Bouldin, T. W. (PI)

  National Institute of Environmental Health Sciences

  1/10/94 → 30/9/96

  Project: Research Project

  • Blood Nerve Barrier 100%
  • Injury 66%
  • Toxic Neuropathy 66%
  • Nerve Fiber Degeneration 50%
  • Toxicants 38%

• NATURAL KILLER CELL ACTIVITY AND POSTPARTUM MOOD

  Pedersen, C. A. (PI) & Pedersen, C. A. (PI)

  National Center for Research Resources

  1/10/94 → 30/9/96

  Project: Research Project

  • Postpartum Mood 100%
  • Natural Killer Cell 50%
  • Cell Activity 33%
  • Immune Alterations 16%
  • Immune System 16%

• CORE--ANIMAL MODELS

  Krigman, M. R. (PI)

  National Institute of Environmental Health Sciences

  1/10/94 → 30/9/96

  Project: Research Project

  • Model Maintenance 100%
  • Dosing Regimen 100%
  • Record Keeping 50%
  • Toxicants 50%
  • Dose Models 50%

• LIPOPROTEIN AND MACROPHAGE INVOLVEMENT IN NERVE INJURY AND REPAIR

  Goodrum, J. F. (PI)

  National Institute of Environmental Health Sciences

  1/10/94 → 30/9/96

  Project: Research Project

  • Myelin 75%
  • Cholesterol 60%
  • Peripheral Nervous System 50%
  • Apolipoprotein E 40%
  • Neuropathy 40%

• METABOLISM AND GENE EXPRESSION IN TOXIC NEUROPATHIES

  Morell, P. (PI)

  National Institute of Environmental Health Sciences

  1/10/94 → 30/9/96

  Project: Research Project

  • Gene Expression 100%
  • Myelin 100%
  • Metabolic Pathway 100%
  • Neuropathy 100%
  • Myelin Protein 75%

• Purchase of an X-ray Diffractometer

  Osteryoung, R. R. A. (PI)

  National Science Foundation

  15/4/95 → 30/9/96

  Project: Research Project

  • X-ray Diffractometer 100%
  • Homochiral 50%
  • Conducting Materials 50%
  • Spatial Arrangement 50%
  • Magnetic Materials 50%

• MECHANISMS OF PESTICIDE INTERACTIONS--MONOOXYGENASE ENZYMES

  Hodgson, E. (PI)

  National Institute of Environmental Health Sciences

  1/10/84 → 30/9/96

  Project: Research Project

  • Pesticides 100%
  • Pesticide Interactions 33%
  • Xenobiotics 33%
  • Cytochrome P450 (CYP450) 20%
  • P450 20%

• STRATMAN: A Generic Architecture for Intelligent Networked Colocation in Concurrent Engineering

  Bowen, J. A. J. A. (PI) & Franzon, P. P. D. (CoPI)

  National Science Foundation

  1/10/92 → 30/9/96

  Project: Research Project

  • Concurrent Engineering 100%
  • Generic Architecture 100%
  • Constraint Network 33%
  • Alternative Mode 33%
  • Specification Language 33%

• PESTICIDE PERCUTANEOUS ABSORPTION, METABOLISM AND CUTANEOUS TOXICITY

  Guthrie, F. E. (PI)

  National Institute of Environmental Health Sciences

  1/10/84 → 30/9/96

  Project: Research Project

  • Pig 100%
  • Pesticides 99%
  • Skin Flap 77%
  • Toxicants 66%
  • Biotransformation 58%

• ARI: Acquisition of Instrumentation for Optical and Mechanical Surface Characterization

  Dow, T. T. A. (PI)

  National Science Foundation

  1/10/95 → 30/9/96

  Project: Research Project

  • Optical Surface 100%
  • Mechanical Surface 100%
  • Diamond 100%
  • Precision Engineering 100%
  • Tribological Surface 50%

• Mathematical Sciences: Topics in Markov Decision Processes

  Yushkevich, A. A. (PI)

  National Science Foundation

  15/10/94 → 30/9/96

  Project: Research Project

  • Markov Decision Process 100%
  • Borel State Space 28%
  • Average Criterion 14%
  • Long-run Average Cost 14%
  • Management Science 14%

• NEUROBIOLOGY OF COGNITIVE DEVELOPMENT--LATENT INHIBITION

  Carter, C. S. (CoPI)

  National Institute of Mental Health

  1/11/95 → 31/10/96

  Project: Research Project

  • Neurobiology 66%
  • Latent Inhibition 66%
  • Behavior (Neuroscience) 50%
  • Eyelid 33%
  • Ontogeny 33%

• Renovation of UNCW Chemistry Laboratory Facilities

  Moss, M. M. K. (PI) & Martin, N. N. H. (CoPI)

  National Science Foundation

  15/9/93 → 31/10/96

  Project: Research Project

  • Chemistry Laboratory 100%
  • Fume Hood 100%
  • University of North Carolina 50%
  • Four-year-olds 50%
  • Transition Period 50%

• Lysosomal Proenzyme Sorting: A New Receptor

  Erickson, A. A. H. (PI)

  National Science Foundation

  1/11/92 → 31/10/96

  Project: Research Project

  • Enzyme 100%
  • Eicosanoid Receptor 100%
  • Proenzymes 100%
  • Lysosome 75%
  • Amino Acids 37%